Teriparatide
Also known as: Forteo, PTH 1-34, Parathyroid Hormone 1-34
- Half-life:
- ~1 hour
Administration Routes
Mechanism of Action
Recombinant PTH 1-34; when given intermittently, preferentially activates osteoblasts over osteoclasts; increases bone remodeling and net bone formation; stimulates IGF-1 in bone
FDA-approved parathyroid hormone fragment for severe osteoporosis. The only anabolic bone treatment (builds new bone vs. just preventing loss). Used by longevity physicians for bone density optimization.
Primary Research Areas
- bone formation
- bone density increase
- osteoporosis reversal
- fracture risk reduction
Risk Profile
Moderate risk profile in research contexts. Consult a healthcare professional before use.
Regulatory Status
FDA-approved parathyroid hormone 1-34 analog. Forteo (NDA 021318, Nov 2002) for osteoporosis. Biosimilar Bonsity (NDA 210842, Jan 2020) also approved. Prescription only.
Effective: November 26, 2002View FDA source →
Regulatory status reflects publicly available information and may change. This is not legal or medical advice.
Where to Find Teriparatide
No active associated providers listed yet.