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LongevityMedium Risk

Teriparatide

Also known as: Forteo, PTH 1-34, Parathyroid Hormone 1-34

Half-life:
~1 hour

Administration Routes

subcutaneous injection
PeptideBase provides educational research tools and provider discovery. It does not provide medical advice, diagnosis, treatment, prescribing guidance, or dosing instructions. Consult a qualified healthcare professional before making health decisions.

Mechanism of Action

Recombinant PTH 1-34; when given intermittently, preferentially activates osteoblasts over osteoclasts; increases bone remodeling and net bone formation; stimulates IGF-1 in bone

FDA-approved parathyroid hormone fragment for severe osteoporosis. The only anabolic bone treatment (builds new bone vs. just preventing loss). Used by longevity physicians for bone density optimization.

Primary Research Areas

  • bone formation
  • bone density increase
  • osteoporosis reversal
  • fracture risk reduction

Risk Profile

Medium Risk

Moderate risk profile in research contexts. Consult a healthcare professional before use.

Regulatory Status

Prescription OnlyFDA Approved

FDA-approved parathyroid hormone 1-34 analog. Forteo (NDA 021318, Nov 2002) for osteoporosis. Biosimilar Bonsity (NDA 210842, Jan 2020) also approved. Prescription only.

Effective: November 26, 2002View FDA source →

Regulatory status reflects publicly available information and may change. This is not legal or medical advice.

Where to Find Teriparatide

No active associated providers listed yet.