Peptides

Advanced Obesity Drug 9604, hGH Fragment 176-191

AOD-9604 is a synthetic fragment of the human growth hormone molecule, corresponding to amino acids 176–191 of the C-terminus. It is researched specifically for its lipolytic properties and is considered a lower-risk alternative to full growth hormone analogues for body composition research, given its apparent lack of effect on insulin sensitivity or IGF-1 levels.

CJC-1295 DAC, Drug Affinity Complex GHRH

CJC-1295 is a synthetic analogue of growth hormone-releasing hormone (GHRH). The DAC (Drug Affinity Complex) form binds to albumin in the bloodstream, extending its half-life to several days and enabling sustained elevation of GH and IGF-1 levels. It is commonly researched alongside GHRP peptides for body composition and recovery outcomes.

Ozempic, Wegovy, Rybelsus

Semaglutide is a GLP-1 receptor agonist approved by the FDA for type 2 diabetes (Ozempic) and chronic weight management (Wegovy). It is among the most prescribed and searched compounds in the weight loss space. Compounding pharmacies have produced semaglutide formulations under 503A and 503B frameworks, with significant provider interest across the telehealth and functional medicine space. Its mechanism involves both peripheral and central appetite suppression.

Egrifta, TH9507

Tesamorelin is a stabilised analogue of endogenous growth hormone-releasing hormone (GHRH). It holds FDA approval for the treatment of HIV-associated lipodystrophy and is the most clinically studied GHRH analogue. Outside its approved indication, it is researched for visceral fat reduction, cognitive function, and metabolic health in older adults.

Mounjaro, Zepbound, Dual GLP-1

Tirzepatide is a once-weekly injectable dual agonist of GLP-1 and GIP receptors, FDA approved for type 2 diabetes (Mounjaro) and weight management (Zepbound). Clinical trials demonstrate weight reductions exceeding those seen with semaglutide in head-to-head comparisons. Compounded formulations are offered by telehealth and functional medicine providers across the US. It represents the current clinical frontier in pharmacological weight management.

Epitalon, Epithalamin, Ala-Glu-Asp-Gly

Epithalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed from research into the pineal gland peptide complex epithalamin. It is researched for its role in regulating melatonin secretion, antioxidant enzyme activity, and telomere dynamics, with a body of work primarily from Russian research groups.

NAD, Nicotinamide Adenine Dinucleotide, NAD+ IV Therapy

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every cell, central to energy production, DNA repair, and sirtuin activation. While not a peptide in the traditional sense, it is widely administered by functional medicine and longevity providers via intravenous infusion or subcutaneous injection. Research interest centres on its role in mitochondrial health, cellular resilience, and neurological function as NAD+ levels decline with age.

Body Protection Compound 157, PL 14736

BPC-157 is a synthetic pentadecapeptide derived from a protective protein found in human gastric juice. It is commonly researched for its role in soft tissue repair, particularly in tendons, ligaments, and muscle following injury or high training loads. Early research suggests it may also support gut integrity and systemic healing.

Thymosin Beta-4, Tβ4

TB-500 is a synthetic version of Thymosin Beta-4, a naturally occurring peptide found in nearly all human cells. It is researched for its role in promoting cellular repair, angiogenesis, and immune modulation, particularly in the context of musculoskeletal recovery and tissue healing after acute injury.

Tα1, Zadaxin

Thymosin Alpha-1 (Tα1) is a naturally occurring peptide produced by the thymus gland and present at low levels in peripheral blood. It is primarily researched for immune-modulatory effects, including support for post-illness recovery and long-term immune resilience. It has been used in clinical settings for chronic hepatitis and immunodeficiency conditions.

TP-7

Selank is a synthetic heptapeptide analogue of tuftsin. Developed in Russia alongside Semax, it is researched for its anxiolytic and nootropic properties without the sedative effects associated with benzodiazepines. It is commonly studied for stress reduction, anxiety management, and cognitive performance in high-demand environments.

ACTH(4-10) analogue, Meksidol

Semax is a heptapeptide analogue of the adrenocorticotropic hormone fragment ACTH(4-10), developed in Russia. It has been approved for use in Russia and Ukraine for cognitive enhancement and neuroprotection. It is researched for nootropic, anxiolytic, and neuroprotective properties in the context of focus, stress resilience, and cognitive performance.

NNC 26-0161

Ipamorelin is a selective growth hormone secretagogue and ghrelin receptor agonist. It stimulates pulsatile GH release from the anterior pituitary with high selectivity — producing minimal effect on cortisol, prolactin, or ACTH compared to earlier GHRPs. It is commonly researched for its role in supporting body composition, recovery, and lean mass maintenance.

Ibutamoren, MK-0677, Nutrobal

MK-677 (Ibutamoren) is an orally active, non-peptide ghrelin receptor agonist and growth hormone secretagogue. Unlike injectable GH peptides, it is taken orally and provides sustained elevation of GH and IGF-1 levels throughout the day. It is commonly researched for muscle and body composition outcomes, and is of particular interest for users who prefer oral administration routes.

GHRH 1-29, Sermorelin Acetate, Geref

Sermorelin is a GHRH analogue used to stimulate endogenous growth hormone production. It is one of the most widely prescribed peptides in the anti-aging and functional medicine space, valued for preserving the natural pituitary feedback axis while supporting body composition, sleep quality, and tissue repair. Compounded formulations are available in the US through 503A pharmacies.

Copper Peptide, Tripeptide-1 Copper, Glycyl-L-Histidyl-L-Lysine Copper

GHK-Cu (copper peptide tripeptide-1) is a naturally occurring plasma copper complex with broad tissue-remodelling activity. It is one of the most extensively researched peptides for skin health, wound healing, and collagen synthesis. Research has explored its effects across dermatological, cosmetic, and systemic contexts, including roles in joint tissue maintenance and anti-inflammatory signalling.

Bremelanotide, Vyleesi

PT-141 (bremelanotide) is a melanocortin receptor agonist researched for its effects on sexual function in both men and women. It acts centrally via the hypothalamus rather than through vascular mechanisms, distinguishing it from PDE5 inhibitors. It received FDA approval as Vyleesi for HSDD in premenopausal women and is also used off-label in compounded form. Common side effects include transient nausea and flushing.