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PerformanceLow Risk

Ipamorelin

Also known as: NNC 26-0161

Half-life:
2 hours

Administration Routes

subcutaneous
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Mechanism of Action

Ipamorelin binds to the ghrelin receptor (GHSR-1a) and stimulates dose-dependent GH release with a clean hormonal profile. Unlike GHRP-6 or hexarelin, it does not significantly stimulate appetite-related pathways or cortisol secretion at standard research doses. This selectivity makes it a frequently studied peptide for protocols where hormonal side-effect profiles are a consideration.

Ipamorelin is a selective growth hormone secretagogue and ghrelin receptor agonist. It stimulates pulsatile GH release from the anterior pituitary with high selectivity — producing minimal effect on cortisol, prolactin, or ACTH compared to earlier GHRPs. It is commonly researched for its role in supporting body composition, recovery, and lean mass maintenance.

Primary Research Areas

  • performance
  • fat_loss
  • recovery

Risk Profile

Low Risk

Generally considered lower risk in research contexts. Consult a healthcare professional before use.

Providers Offering Ipamorelin