Back to Peptides
sexual_healthLow Risk

Gonadorelin

Also known as: GnRH, Luteinizing Hormone-Releasing Hormone, LHRH

Half-life:
~2-4 minutes

Administration Routes

subcutaneous injectionintravenous
PeptideBase provides educational research tools and provider discovery. It does not provide medical advice, diagnosis, treatment, prescribing guidance, or dosing instructions. Consult a qualified healthcare professional before making health decisions.

Mechanism of Action

Synthetic GnRH that binds pituitary GnRH receptors; pulsatile dosing stimulates LH/FSH release; used to maintain HPG axis during TRT

Synthetic GnRH used to maintain pituitary-gonadal axis function, particularly during testosterone replacement therapy. Prevents testicular atrophy and preserves fertility.

Primary Research Areas

  • LH/FSH stimulation
  • testicular function maintenance
  • testosterone production
  • fertility support

Risk Profile

Low Risk

Generally considered lower risk in research contexts. Consult a healthcare professional before use.

Regulatory Status

CompoundableNot Evaluated by FDA

Previously FDA-approved as Factrel (NDA 017019). Voluntarily discontinued by manufacturer. On FDA 503A Category 1 bulk drug substances list for compounding. Prescription compounded product.

Regulatory status reflects publicly available information and may change. This is not legal or medical advice.

Where to Find Gonadorelin