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Peptide Comparison

Angiotensin (1-7) vs Sermorelin

Angiotensin (1-7)

Ang-(1-7)

LongevityInvestigationalResearch Only

Half-life: ~9–10 sec (rat)

No providers listed yet

Full Angiotensin (1-7) profile →
vs

Sermorelin

GHRH 1-29

PerformanceUnder clinical reviewPrescription

Half-life: 10–20 minutes

473 providers listed

Full Sermorelin profile →
Bottom line

Angiotensin (1-7) and Sermorelin target different goals — Angiotensin (1-7) for cardiovascular protection, Sermorelin for pulsatile GH release via direct GHRH receptor agonism at the pituitary. They're compared here for reference, not as direct substitutes.

Quick Verdict

Angiotensin (1-7)

Half-life

~9–10 sec (rat)

Sermorelin

Half-life

10–20 minutes

Different Goals

Angiotensin (1-7) and Sermorelin target different goals — Angiotensin (1-7) for Longevity & Cellular, Sermorelin for GH / IGF Axis. They're compared here for reference; there isn't a single “better” choice between them.

Side-by-Side Comparison
Angiotensin (1-7)
Sermorelin
Mechanism Family
Longevity & Cellular
GH / IGF Axis
Half-life
~9–10 sec (rat)
10–20 minutes
FDA Status
investigational
Under clinical review
Admin Routes
subcutaneous, intravenous
subcutaneous
Availability
Research Only
Prescription
Providers
None listed
473 listed
Avail. Notes
—
Previously FDA-approved for pediatric GH deficiency (Geref); approval withdrawn 2008. Its bulk substance appears on the FDA 503B outsourcing-facility list (Category 1) but not the 503A pharmacy bulk-substances list; compounded-product availability historically rested on the former approved-drug status.
Research Evidence

Angiotensin (1-7)

RCT · 9 key studies · most recent 2026

Sermorelin

RCT · 3 key studies · most recent 2026
Research Citations

About Angiotensin (1-7)

Binds Mas receptor (MasR), activating nitric oxide synthase and reducing oxidative stress. Opposes TGF-β and angiotensin II signaling to reduce fibrosis. Enhances insulin sensitivity and provides cardiovascular protection.

Research Areas
cardiovascular protectionanti-fibroticvasodilationinsulin sensitivitykidney protection

About Sermorelin

Sermorelin is a synthetic analogue of the first 29 amino acids of endogenous growth hormone-releasing hormone (GHRH). It binds to GHRH receptors on pituitary somatotrophs, stimulating pulsatile GH secretion in a physiological pattern that preserves the natural hypothalamic-pituitary feedback axis — contrasting with direct GH administration. Downstream IGF-1 elevation mediates many of its body composition, tissue-repair, and sleep quality effects.

Research Areas
pulsatile GH release via direct GHRH receptor agonism at the pituitaryendogenous GH axis restoration — preserves natural pulse patterns unlike exogenous GHlean mass, sleep quality, and metabolic improvements in anti-aging clinical researchsubcutaneous injection — widely available through telehealth anti-aging providers
Safety Profile

Information below reflects published research data only — not medical advice. Consult a qualified provider before use.

Angiotensin (1-7)

No established clinical contraindications. This is an investigational compound with limited human data and has not been evaluated by the FDA for safety in this context. Consult a qualified clinician.

Sermorelin

Absolute Contraindications

Under clinical review

Being verified by our medical team before we display contraindications for this peptide.

Suggested Monitoring
IGF-1Fasting glucoseHbA1cInsulin

Sermorelin clinical protocols measure IGF-1 as the primary marker of GH axis response. Fasting glucose and insulin are standard baseline assessments given GH's effect on insulin sensitivity.

Used Together?

Sermorelin

  • Ipamorelin

    Research suggests Sermorelin and Ipamorelin may produce complementary growth hormone release effects when combined. Sermorelin acts as a GHRH analogue via pituitary receptors, while Ipamorelin acts via ghrelin receptors — dual-pathway stimulation studied in GH optimization research.

Price (per mg)

Angiotensin (1-7)

Not enough vendor pricing yet.

Sermorelin

$8.40/mg

$6.92 – $10.57 range

63 vendors

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Where to source these peptides

PeptideBase lists providers for educational research purposes only. Always consult a qualified healthcare professional before obtaining or using any peptide.

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Educational research tools — not medical advice.

Cite this page

Data last updated October 26, 2026

Free to reference and republish with attribution to PeptideBase. Choose a format:

PeptideBase. (2026). Angiotensin (1-7) vs Sermorelin — Per-mg Price Comparison. Retrieved October 27, 2026, from https://peptidebase.io/peptides/compare/angiotensin-1-7/sermorelin

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