RecoveryMedium Risk

Alpha-MSH

Also known as: Alpha-Melanocyte Stimulating Hormone, α-MSH

Half-life:: ~3-5 minutes (plasma)

Administration Routes

subcutaneous injectionintranasal

PeptideBase provides educational research tools and provider discovery. It does not provide medical advice, diagnosis, treatment, prescribing guidance, or dosing instructions. Consult a qualified healthcare professional before making health decisions.

Mechanism of Action

Melanocortin peptide; activates MC1R (pigmentation/anti-inflammatory), MC3R (energy balance), MC4R (appetite); suppresses NF-κB and pro-inflammatory cytokines

The parent melanocortin peptide from which KPV is derived. Regulates inflammation, appetite, and body temperature through MC receptor subtypes. Studied for inflammatory and autoimmune conditions.

Primary Research Areas

anti-inflammatory
appetite suppression
thermoregulation
skin pigmentation

Risk Profile

Medium Risk

Moderate risk profile in research contexts. Consult a healthcare professional before use.

Regulatory Status

Research OnlyNot Evaluated by FDA

Endogenous 13-aa neuropeptide. No FDA-approved drug. Bremelanotide (PT-141/Vyleesi) is an approved derivative but a distinct compound. Not on FDA 503A bulks list. Research use only.

Regulatory status reflects publicly available information and may change. This is not legal or medical advice.

Where to Find Alpha-MSH

No active associated providers listed yet.