AICAR vs GHRP-6

Converted intracellularly to ZMP, a potent AMPK activator. AMPK activation increases fatty acid oxidation, glucose uptake, and mitochondrial biogenesis — the same metabolic pathways activated by sustained aerobic exercise.

A cell-permeable nucleoside analog that activates AMPK, mimicking cellular exercise signals. Studied for endurance enhancement and metabolic disease research. Not a true peptide — a synthetic nucleoside frequently sold by peptide vendors.

Ghrelin receptor agonist; stimulates pituitary GH release and increases appetite via hypothalamic ghrelin pathways

A hexapeptide that strongly stimulates growth hormone release while also increasing appetite. Commonly used for muscle gain and recovery.