Is Humanin FDA approved?

Humanin is not evaluated or approved by the FDA. It is discussed for research and educational purposes only, not as medical guidance.

How is Cerluten administered in research settings?

In research settings, Cerluten is typically administered via the oral or subcutaneous routes. PeptideBase does not provide dosing or administration instructions.

How is Humanin administered in research settings?

In research settings, Humanin is typically administered via the subcutaneous or intranasal routes. PeptideBase does not provide dosing or administration instructions.

Home›Research›Compare›Cerluten vs Humanin

Peptide Comparison

Cerluten vs Humanin

Q: What is the difference between Cerluten and Humanin?

Cerluten: CNS-targeted peptide complex that modulates neuronal gene expression. Shown in Russian clinical studies to improve memory consolidation, attention, and protect against neurodegeneration. Humanin: Mitochondria-derived peptide; binds gp130 receptor, activates STAT3/JAK pathway; inhibits BAX-mediated apoptosis; improves insulin sensitivity

Both are Longevity & Cellular peptides.

Cerluten

brain peptide bioregulator

LongevityResearch Only

1 providers listed

Full Cerluten profile →

Humanin

LongevityNot EvaluatedResearch Only

Half-life: ~2-4 hours

9 providers listed

Full Humanin profile →

Bottom line

Humanin carries stronger published evidence (Cohort study, 11 key studies) than Cerluten (Review, 2); both are research compounds.

Quick Verdict

Cerluten

Evidence

Review-level

Half-life

—

Humanin

Evidence

Emerging Clinical

Half-life

~2-4 hours

Which One Should You Choose?

Your goal	Better option
Stronger clinical evidence	Humanin
Oral administration option	Cerluten
More provider options (1 vs 9)	Humanin

Research summary only — not medical advice. Consult a qualified provider before making any decisions.

Side-by-Side Comparison

Cerluten

Humanin

Mechanism Family

Longevity & Cellular

Half-life

—

~2-4 hours

FDA Status

unknown

not evaluated

Admin Routes

oral, subcutaneous

subcutaneous, intranasal

Availability

Research Only

Providers

1 listed

9 listed

Avail. Notes

—

Mitochondria-derived 21-aa cytoprotective peptide encoded in 12S rRNA. No FDA approval, no NDA or IND. Research interest in aging and neuroprotection. Research use only.

Research Evidence

Cerluten

Review-levelReview · 2 key studies · most recent 2022

Humanin

Emerging ClinicalCohort study · 11 key studies · most recent 2026

Research Citations

Cerluten

Review2022 · International Journal of Molecular Sciences

Peptide Regulation of Gene Expression and Protein Synthesis in Bronchial Epithelium

Review2021 · Molecules

Peptide Regulation of Gene Expression: A Systematic Review

Humanin

Cohort2026 · Biomedicines

Humanin and MOTS-c Attenuate Atrial Fibrillation by Suppressing Fibrosis and Mitochondrial Dysfunction.

Cohort2026 · Aging Cell

Humanin Mitigates Aβ-Induced Retinal Pigment Epithelium Injury via AMPK-Beclin1-Dependent Mitophagy.

Cohort2026 · Metabolites

Humanin Restores Metabolic Hormone Homeostasis of Leptin, Ghrelin, Irisin and Asprosin in Streptozotocin-Indu…

Cohort2026 · Am J Respir Cell Mol Biol

Mitochondrial-derived Peptides and Cytoprotection in ARDS: Emerging Therapeutic Promise of Humanin.

+7 more

About Cerluten

CNS-targeted peptide complex that modulates neuronal gene expression. Shown in Russian clinical studies to improve memory consolidation, attention, and protect against neurodegeneration.

Research Areas

neuroprotectioncognitive supportmemoryanti-aginglongevity

About Humanin

Mitochondria-derived peptide; binds gp130 receptor, activates STAT3/JAK pathway; inhibits BAX-mediated apoptosis; improves insulin sensitivity

Research Areas

neuroprotectionanti-apoptoticmetabolic improvementcardiovascular protection

Safety Profile

Information below reflects published research data only — not medical advice. Consult a qualified provider before use.

Cerluten

No established clinical contraindications. This is an investigational compound with limited human data and has not been evaluated by the FDA for safety in this context. Consult a qualified clinician.

Humanin

No established clinical contraindications. This is an investigational compound with limited human data and has not been evaluated by the FDA for safety in this context. Consult a qualified clinician.

Find Providers

Where to source these peptides

Providers offering

Cerluten

1 listed

Browse directory →

Providers offering

Humanin

9 listed

Browse directory →

PeptideBase lists providers for educational research purposes only. Always consult a qualified healthcare professional before obtaining or using any peptide.

More Longevity & Cellular Comparisons

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Educational research tools — not medical advice.