Leuphasyl vs Matrixyl

Tetrapeptide that mimics enkephalin to modulate facial muscle contraction; competes with enkephalin for opioid receptor sites in neuromuscular junctions; reduces repetitive muscle micro-contractions

A neuromodulating peptide that reduces expression lines via the enkephalin pathway, distinct from SNARE-inhibiting peptides (Argireline, SNAP-8). Complements those actives through a different mechanism.

Palmitoylated pentapeptide fragment of collagen I; binds TGF-β receptors on fibroblasts; upregulates collagen I, III, and fibronectin; procollagen production via MAPK pathway

The original and most clinically validated cosmeceutical peptide. A fatty acid-conjugated collagen fragment that directly stimulates fibroblasts to produce new collagen. Validated in multiple clinical trials.