Argireline vs Leuphasyl

Inhibits SNARE complex formation in facial muscles; reduces acetylcholine release locally; relaxes expression lines without systemic effects

A topical peptide that reduces the appearance of expression lines by mimicking botulinum toxin's mechanism locally. Popular cosmeceutical ingredient.

Tetrapeptide that mimics enkephalin to modulate facial muscle contraction; competes with enkephalin for opioid receptor sites in neuromuscular junctions; reduces repetitive muscle micro-contractions

A neuromodulating peptide that reduces expression lines via the enkephalin pathway, distinct from SNARE-inhibiting peptides (Argireline, SNAP-8). Complements those actives through a different mechanism.