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Skin & JointLow Risk

Leuphasyl

Also known as: Acetyl Tetrapeptide-2, Tyr-D-Arg-Phe-beta-Ala-NH2

Half-life:
N/A (topical)

Administration Routes

topical
PeptideBase provides educational research tools and provider discovery. It does not provide medical advice, diagnosis, treatment, prescribing guidance, or dosing instructions. Consult a qualified healthcare professional before making health decisions.

Mechanism of Action

Tetrapeptide that mimics enkephalin to modulate facial muscle contraction; competes with enkephalin for opioid receptor sites in neuromuscular junctions; reduces repetitive muscle micro-contractions

A neuromodulating peptide that reduces expression lines via the enkephalin pathway, distinct from SNARE-inhibiting peptides (Argireline, SNAP-8). Complements those actives through a different mechanism.

Primary Research Areas

  • expression line reduction
  • facial muscle relaxation
  • enkephalin pathway modulation

Risk Profile

Low Risk

Generally considered lower risk in research contexts. Consult a healthcare professional before use.

Regulatory Status

Research OnlyNot Evaluated by FDA

Cosmetic peptide (pentapeptide-18), enkephalin analog. Sold as cosmetic anti-wrinkle ingredient. Not regulated as a drug by FDA. No NDA or IND. Cosmetic use only.

Regulatory status reflects publicly available information and may change. This is not legal or medical advice.

Where to Find Leuphasyl

No active associated providers listed yet.