About Relaxin
Binds RXFP1 receptor, activating adenylyl cyclase and cAMP/PKA pathway. Upregulates matrix metalloproteinases (MMPs) to degrade excess collagen. Inhibits TGF-β fibrotic signaling. Promotes cervical softening and pelvic ligament compliance.
A peptide hormone produced by the corpus luteum during pregnancy and in small amounts in non-pregnant individuals. Remodels connective tissue, relaxes pelvic ligaments, and has potent anti-fibrotic effects. Studied for pelvic floor dysfunction, fertility support, and cardiac fibrosis.
Research Areas
Regulatory & Evidence
Risk Profile
Moderate risk profile in research contexts. Review contraindications and administration guidelines before use.
Regulatory Status
- Availability Status
- Research Only
Regulatory status reflects publicly available information and may change. This is not legal or medical advice.
Safety Notes
Moderate risk profile. Review all reported considerations carefully before use.
Reported contraindications & considerations
Consult a qualified healthcare professional before making any health decisions. This information is educational only and does not constitute medical advice.
Where to Find Relaxin
Coverage expanding
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Frequently Asked Questions — Relaxin
A peptide hormone produced by the corpus luteum during pregnancy and in small amounts in non-pregnant individuals. Remodels connective tissue, relaxes pelvic ligaments, and has potent anti-fibrotic effects.
connective tissue remodeling, anti-fibrotic, pelvic floor support, fertility support, cardiac protection.