Home›Research›Compare›Alpha-MSH vs Relaxin
Peptide ComparisonAlpha-MSH vs Relaxin
Both are Reproductive & Hormonal peptides.
Alpha-MSH
Alpha-Melanocyte Stimulating Hormone
Half-life: ~3-5 minutes (plasma)
No providers listed yet
Relaxin
Relaxin-2
Half-life: ~7–8 h (terminal, serelaxin/rh-relaxin-2)
No providers listed yet
Relaxin carries stronger published evidence (RCT, 5 key studies) than Alpha-MSH (Review, 12); both are research compounds.
Alpha-MSH
Half-life
~3-5 minutes (plasma)
Relaxin
Half-life
~7–8 h (terminal, serelaxin/rh-relaxin-2)
| Your goal | Better option |
|---|---|
| Stronger clinical evidence | Relaxin |
| Further along in FDA review | Relaxin |
Research summary only — not medical advice. Consult a qualified provider before making any decisions.
Alpha-MSH
Relaxin
Alpha-MSH
Preclinical assessment of (177)Lu-DOTA-Pip-Nle-CycMSH(hex): In vivo evaluation and human dosimetry estimation.
Antrodia cinnamomea extract exhibits anti-melanogenic and anti-photoaging effects: potential for cosmetic and…
Depigmenting Effects of Vitex rotundifolia Cone Essential Oil in Melanocytes and Its Chemical Composition.
Hypothalamic orexigenic and anorexigenic neuropeptides in the rotenone model of Parkinson's disease.
+8 more
Relaxin
Development of a long-acting relaxin for the treatment of pulmonary hypertension.
Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, place…
Association of Relaxin-1 Levels with Mortality in Sepsis and Septic Shock.
Serelaxin has greater anti-fibrotic potential than perindopril but maintains its anti-fibrotic efficacy in th…
+1 more
About Alpha-MSH
Melanocortin peptide; activates MC1R (pigmentation/anti-inflammatory), MC3R (energy balance), MC4R (appetite); suppresses NF-κB and pro-inflammatory cytokines
About Relaxin
Binds RXFP1 receptor, activating adenylyl cyclase and cAMP/PKA pathway. Upregulates matrix metalloproteinases (MMPs) to degrade excess collagen. Inhibits TGF-β fibrotic signaling. Promotes cervical softening and pelvic ligament compliance.
Information below reflects published research data only — not medical advice. Consult a qualified provider before use.
Alpha-MSH
No established clinical contraindications
Relaxin
No established clinical contraindications. This is an investigational compound with limited human data and has not been evaluated by the FDA for safety in this context. Consult a qualified clinician.
Where to source these peptides
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