Guides
How-to guides, research breakdowns, and reference articles on peptides, providers, and compounding pharmacies.
Provider & Compliance Guides
How PeptideBase Verifies Providers
The PeptideBase directory lists 3,136 active providers. Here's exactly what we check — and what we don't — before we assign a verified badge.
Read guide →6 minBPC-157 Legal Status 2026: State-by-State Guide + 14-State Provider Map
Federal and state law diverge on BPC-157. This guide covers FDA classification, compounding pharmacy vs. research vendor access, and state-specific provider counts across 14 states.
Read guide →14 minHow to find a legitimate peptide provider: the verification checklist most guides skip
An eight-step checklist for vetting peptide providers — licensing lookups, COA verification, telehealth evaluation, and the red flags that should stop the process.
Read guide →13 min503A vs 503B Compounding Pharmacies: What's the Difference?
Not all compounding pharmacies are the same. 503A and 503B pharmacies operate under entirely different FDA frameworks — with different oversight, quality standards, and access rules. Here's what the distinction means for peptide therapy.
Read guide →5 minResearch Peptide Vendors: What COA and HPLC Testing Actually Mean
Certificate of Analysis and HPLC testing are the two most cited quality signals in the research peptide vendor space. Here is what they actually measure, what to look for, and what they cannot tell you.
Read guide →8 minHow to Find a 503A Compounding Pharmacy for Peptides
How to find a legitimate 503A compounding pharmacy for peptides: what to verify, what to ask about sterile compounding, and red flags to watch for.
Read guide →8 min
Research Guides
Five Signals That a Longevity Research Project Is Worth Your Time
PeptideBase analyzed 545+ longevity providers to identify the signals that separate credible DeSci research projects from noise. Here's the framework.
Read guide →9 minWhat Is TB-500 (Thymosin Beta-4)? Research, Effects & Providers
TB-500 is a synthetic peptide based on Thymosin Beta-4, a naturally occurring protein found in virtually every human cell. This guide covers the research, how it works, safety considerations, and how to find a verified provider.
Read guide →5 minPT-141 (Bremelanotide): What the Research Shows
PT-141 is a synthetic melanocortin receptor agonist studied for sexual dysfunction in both men and women. Unlike PDE5 inhibitors, it acts centrally through the nervous system rather than directly on vascular tissue.
Read guide →7 minSemaglutide vs Tirzepatide: Mechanisms, Outcomes, and the Compounding Pharmacy Landscape
Semaglutide and tirzepatide compared on mechanism, trial outcomes, and 2026 provider availability — including live directory data on 637 semaglutide and 423 tirzepatide providers by type.
Read guide →13 minNAD+: What the Research Shows About Cellular Energy and Longevity
NAD+ levels decline measurably with age. Here is what the published research says about IV and subcutaneous administration — and why functional medicine providers have made it a cornerstone of longevity protocols.
Read guide →6 minBPC-157: What the Research Shows About This Recovery Peptide
Three decades of animal model research on BPC-157 — mechanisms, evidence quality by area, why human trials are limited, and 2026 provider availability data from 445 verified directory listings.
Read guide →13 min