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Skin & JointLow Risk

Argireline

Also known as: Acetyl Hexapeptide-3, Acetyl Hexapeptide-8

Half-life:
N/A (topical)

Administration Routes

topical
PeptideBase provides educational research tools and provider discovery. It does not provide medical advice, diagnosis, treatment, prescribing guidance, or dosing instructions. Consult a qualified healthcare professional before making health decisions.

Mechanism of Action

Inhibits SNARE complex formation in facial muscles; reduces acetylcholine release locally; relaxes expression lines without systemic effects

A topical peptide that reduces the appearance of expression lines by mimicking botulinum toxin's mechanism locally. Popular cosmeceutical ingredient.

Primary Research Areas

  • wrinkle reduction
  • muscle relaxation (topical)
  • anti-aging skin

Risk Profile

Low Risk

Generally considered lower risk in research contexts. Consult a healthcare professional before use.

Regulatory Status

Research OnlyNot Evaluated by FDA

Cosmetic peptide (acetyl hexapeptide-3). Sold as cosmetic ingredient by Lipotec/Sederma. Not regulated as a drug by FDA. No NDA or IND. Cosmetic anti-wrinkle ingredient only.

Regulatory status reflects publicly available information and may change. This is not legal or medical advice.

Where to Find Argireline