About CGRP
Binds CLR/RAMP1 receptor complex. Causes vasodilation via cAMP/PKA/nitric oxide pathway. Modulates nociceptive signaling in the trigeminal system. Promotes bone healing and has anti-inflammatory effects in peripheral tissues.
A 37-amino acid neuropeptide released from sensory nerve fibers and one of the most potent endogenous vasodilators. Central to migraine pathophysiology and studied for pain modulation, wound healing, and bone repair.
Research Areas
Regulatory & Evidence
Risk Profile
Moderate risk profile in research contexts. Review contraindications and administration guidelines before use.
Regulatory Status
- Availability Status
- Research Only
Regulatory status reflects publicly available information and may change. This is not legal or medical advice.
Safety Notes
Moderate risk profile. Review all reported considerations carefully before use.
Reported contraindications & considerations
Consult a qualified healthcare professional before making any health decisions. This information is educational only and does not constitute medical advice.
Where to Find CGRP
2 providersFrequently Asked Questions — CGRP
A 37-amino acid neuropeptide released from sensory nerve fibers and one of the most potent endogenous vasodilators. Central to migraine pathophysiology and studied for pain modulation, wound healing, and bone repair.
vasodilation, pain modulation, wound healing, bone repair.
2 providers in the directory currently offer CGRP.