Home›Research›Compare›CGRP vs GLP-2
Peptide ComparisonCGRP vs GLP-2
Both are Tissue Repair peptides.
CGRP
Calcitonin Gene-Related Peptide
Half-life: ~3.6 min / ~13.6 min (biphasic; sheep)
2 providers listed
GLP-2
Glucagon-like Peptide-2
11 providers listed
CGRP carries stronger published evidence (RCT, 14 key studies) than GLP-2 (RCT, 8); both are research compounds.
CGRP
Evidence
Half-life
~3.6 min / ~13.6 min (biphasic; sheep)
GLP-2
Evidence
Half-life
—
| Your goal | Better option |
|---|---|
| Stronger clinical evidence | CGRP |
| More provider options (2 vs 11) | GLP-2 |
Research summary only — not medical advice. Consult a qualified provider before making any decisions.
CGRP
GLP-2
CGRP
Efficacy and tolerability of erenumab in patients with episodic migraine in whom two-to-four previous prevent…
A Controlled Trial of Erenumab for Episodic Migraine
Three-year real-world effectiveness, treatment persistence, and planned discontinuation of anti-calcitonin ge…
Astrocyte-Targeted Biomarkers for Calcitonin Gene-Related Peptide-Related Neurovascular Disorders: Insights f…
+10 more
GLP-2
Prostaglandin E2 stimulates GLP-1 and GLP-2 secretion and reduces glucose absorption in the perfused rat smal…
The Role of Vasoactive Intestinal Peptide in Glucagon-like Peptide-2-Mediated Intestinal Lipid Handling.
PERCC1-associated enteropathy: Diagnostic challenges and enteral autonomy achieved with teduglutide.
Early ecological changes in intestinal microbiota with the long-acting GLP-2 analog apraglutide in short bowe…
+4 more
About CGRP
Binds CLR/RAMP1 receptor complex. Causes vasodilation via cAMP/PKA/nitric oxide pathway. Modulates nociceptive signaling in the trigeminal system. Promotes bone healing and has anti-inflammatory effects in peripheral tissues.
About GLP-2
Binds GLP-2 receptor on intestinal enteroendocrine cells. Promotes enterocyte proliferation and reduces apoptosis, increasing villus height and crypt depth. Strengthens tight junctions and reduces intestinal permeability.
Information below reflects published research data only — not medical advice. Consult a qualified provider before use.
CGRP
No structured contraindication profile is available for this compound yet. This compound is FDA-approved — consult the official prescribing information or a qualified clinician.
Under clinical review
Being verified by our medical team before we display monitoring guidance for this peptide.
GLP-2
Under clinical review
Being verified by our medical team before we display contraindications for this peptide.
Under clinical review
Being verified by our medical team before we display monitoring guidance for this peptide.
Where to source these peptides
PeptideBase lists providers for educational research purposes only. Always consult a qualified healthcare professional before obtaining or using any peptide.
More Tissue Repair Comparisons
Browse all peptides →Educational research tools — not medical advice.