Is Ac-SDKP FDA approved?

Ac-SDKP is not evaluated or approved by the FDA. It is discussed for research and educational purposes only, not as medical guidance.

Is GLP-2 FDA approved?

GLP-2 is not evaluated or approved by the FDA. It is discussed for research and educational purposes only, not as medical guidance.

How is Ac-SDKP administered in research settings?

In research settings, Ac-SDKP is typically administered via the subcutaneous or intravenous routes. PeptideBase does not provide dosing or administration instructions.

How is GLP-2 administered in research settings?

In research settings, GLP-2 is typically administered via the subcutaneous route. PeptideBase does not provide dosing or administration instructions.

Home›Research›Compare›Ac-SDKP vs GLP-2

Peptide Comparison

Ac-SDKP vs GLP-2

Q: What is the difference between Ac-SDKP and GLP-2?

Ac-SDKP: Inhibits hematopoietic stem cell entry into S-phase. Blocks TGF-β1-mediated fibroblast activation, reducing collagen deposition. Promotes angiogenesis via VEGF upregulation. Regulated in vivo by ACE enzyme. GLP-2: Binds GLP-2 receptor on intestinal enteroendocrine cells. Promotes enterocyte proliferation and reduces apoptosis, increasing villus height and crypt depth.

Both are Tissue Repair peptides.

Ac-SDKP

N-acetyl-seryl-aspartyl-lysyl-proline

RecoveryNot EvaluatedResearch Only

No providers listed yet

Full Ac-SDKP profile →

GLP-2

Glucagon-like Peptide-2

RecoveryNot EvaluatedResearch Only

11 providers listed

Full GLP-2 profile →

Bottom line

GLP-2 carries stronger published evidence (RCT, 7 key studies) than Ac-SDKP (Animal, 3); both are research compounds.

Quick Verdict

Ac-SDKP

GLP-2

Which One Should You Choose?

Your goal	Better option
Stronger clinical evidence	GLP-2
More provider options (0 vs 11)	GLP-2

Research summary only — not medical advice. Consult a qualified provider before making any decisions.

Side-by-Side Comparison

Ac-SDKP

GLP-2

Mechanism Family

Tissue Repair

Half-life

—

FDA Status

not evaluated

Admin Routes

subcutaneous, intravenous

subcutaneous

Availability

Research Only

Providers

None listed

11 listed

Avail. Notes

—

Native GLP-2 is not an FDA-approved drug substance; an openFDA ingredient search for "glucagon-like" returns no approved product. The approved product is teduglutide (Gattex, NDA 203441, original approval 2012-12-21), a 33-amino-acid ANALOG of human GLP-2 — see the separate teduglutide profile. The 2012-08-30 date previously carried on this record corresponds to no locatable FDA approval action and has been removed.

Research Evidence

Ac-SDKP

Animal · 3 key studies · most recent 2026

GLP-2

RCT · 7 key studies · most recent 2026

Research Citations

Ac-SDKP

Animal2026 · Biomater Adv

Device surface-functionalized ac-SDKP nanoassemblies accelerate endothelial recovery through dual anti-inflam…

Animal2015 · American Journal of Physiology: Renal Physiology

N-Acetyl-Seryl-Aspartyl-Lysyl-Proline: mechanisms of renal protection in mouse model of systemic lupus erythe…

Animal2013 · Kidney International

Thymosin β4 and its degradation product, Ac-SDKP, are novel reparative factors in renal fibrosis

GLP-2

RCT2018 · Nutrition in Clinical Practice

Reduction of Parenteral Nutrition and Hydration Support and Safety With Long-Term Teduglutide Treatment in Pa…

Case series2026 · JPGN Rep

PERCC1-associated enteropathy: Diagnostic challenges and enteral autonomy achieved with teduglutide.

Cohort2026 · Clin Nutr

From childhood to adulthood in chronic intestinal failure: A nationwide study.

Cohort2026 · Clin Nutr

Impact of intestinal resections on the secretion of gastrointestinal hormones.

+3 more

About Ac-SDKP

Inhibits hematopoietic stem cell entry into S-phase. Blocks TGF-β1-mediated fibroblast activation, reducing collagen deposition. Promotes angiogenesis via VEGF upregulation. Regulated in vivo by ACE enzyme.

Research Areas

anti-fibroticcardiac repairwound healingkidney protection

About GLP-2

Binds GLP-2 receptor on intestinal enteroendocrine cells. Promotes enterocyte proliferation and reduces apoptosis, increasing villus height and crypt depth. Strengthens tight junctions and reduces intestinal permeability.

Research Areas

gut lining repairintestinal integritybarrier functionanti-inflammatory

Safety Profile

Information below reflects published research data only — not medical advice. Consult a qualified provider before use.

Ac-SDKP

No established clinical contraindications. This is an investigational compound with limited human data and has not been evaluated by the FDA for safety in this context. Consult a qualified clinician.

GLP-2

Absolute Contraindications

Under clinical review

Being verified by our medical team before we display contraindications for this peptide.

Suggested Monitoring

Under clinical review

Being verified by our medical team before we display monitoring guidance for this peptide.

Find Providers

Where to source these peptides

Providers offering

Ac-SDKP

Browse directory →

Providers offering

GLP-2

11 listed

Browse directory →

PeptideBase lists providers for educational research purposes only. Always consult a qualified healthcare professional before obtaining or using any peptide.

More Tissue Repair Comparisons

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Educational research tools — not medical advice.