About GLP-2
Binds GLP-2 receptor on intestinal enteroendocrine cells. Promotes enterocyte proliferation and reduces apoptosis, increasing villus height and crypt depth. Strengthens tight junctions and reduces intestinal permeability.
A 33-amino acid intestinal peptide co-secreted with GLP-1 from gut L-cells after eating. A potent intestinal trophic factor promoting gut lining integrity, villus growth, and reduced intestinal permeability. Studied for IBD, leaky gut, and gut repair.
Research Areas
gut lining repairintestinal integritybarrier functionanti-inflammatory
Regulatory & Evidence
Risk Profile
Medium Risk
Moderate risk profile in research contexts. Review contraindications and administration guidelines before use.
Regulatory Status
- Availability Status
- Research Only
Regulatory status reflects publicly available information and may change. This is not legal or medical advice.