What is the difference between Cetrorelix and FSH?

Cetrorelix: Competitive GnRH receptor antagonist; immediately blocks pituitary GnRH receptors; rapidly suppresses LH/FSH without initial flare effect; used for controlled hormonal suppression FSH: Binds FSH receptors on Sertoli cells in testes to support sperm maturation and inhibin B production. In women, binds granulosa cell FSH receptors to drive follicular growth and estradiol production.

Is Cetrorelix FDA approved?

Cetrorelix is FDA approved. This regulatory status is provided for research and educational context only.

FSH is FDA approved (FDA status current as of 1997-09-29). This regulatory status is provided for research and educational context only.

How is Cetrorelix administered in research settings?

In research settings, Cetrorelix is typically administered via the subcutaneous route. PeptideBase does not provide dosing or administration instructions.

How is FSH administered in research settings?

In research settings, FSH is typically administered via the subcutaneous or intramuscular routes. PeptideBase does not provide dosing or administration instructions.

Home›Research›Compare›Cetrorelix vs FSH

Peptide Comparison

Cetrorelix vs FSH

Both are Reproductive & Hormonal peptides.

Cetrorelix

Cetrotide

Sexual HealthFDA ApprovedPrescription

Half-life: ~62 hours

1 providers listed

Full Cetrorelix profile →

FSH

Follicle-Stimulating Hormone

Sexual HealthFDA ApprovedPrescription

No providers listed yet

Full FSH profile →

Bottom line

Cetrorelix is carried by more providers on PeptideBase (1 vs 0); otherwise the two are closely matched on the measures we track.

Quick Verdict

Cetrorelix

Half-life

~62 hours

FSH

Half-life

—

Which One Should You Choose?

Your goal	Better option
More provider options (1 vs 0)	Cetrorelix

Research summary only — not medical advice. Consult a qualified provider before making any decisions.

Side-by-Side Comparison

Cetrorelix

FSH

Mechanism Family

Reproductive & Hormonal

Half-life

~62 hours

—

FDA Status

approved

Admin Routes

subcutaneous

subcutaneous, intramuscular

Availability

Prescription

Providers

1 listed

None listed

FDA Update

—

Sep 1997

Avail. Notes

FDA-approved GnRH antagonist. Brand: Cetrotide (NDA 021036, Jun 1999). Prevents premature LH surges in controlled ovarian stimulation. Prescription only.

—

Research Evidence

Cetrorelix

Meta-analysis · 7 key studies · most recent 2026

FSH

Meta-analysis · 9 key studies · most recent 2026

Research Citations

Cetrorelix

Meta-analysis2026 · J Coll Physicians Surg Pak

GnRH Agonists and Antagonists in IVF/ICSI Cycles of PCOS Women: A Network Meta-Analysis.

Meta-analysis2023 · Hum Reprod Update

Optimal GnRH antagonist protocol for ovarian stimulation during ART: systematic review and network meta-analy…

Cohort2026 · Int J Reprod Biomed

Efficacy and safety of different cetrorelix doses in the luteal phase for preventing ovarian hyperstimulation…

Cohort2021 · BMC Pregnancy and Childbirth

Effects of half-dose and full-dose GnRH antagonists on IVF-ET outcomes: a retrospective study

+3 more

FSH

Meta-analysis2026 · J Ovarian Res

The improvement of umbilical cord mesenchymal stem cells on the ovarian microenvironment: a systematic review…

Meta-analysis2011 · Cochrane Database of Systematic Reviews

Recombinant versus urinary gonadotrophin for ovarian stimulation in assisted reproductive technology cycles

Meta-analysis2008 · Reprod Biomed Online

Efficacy and safety of hMG versus recombinant FSH: a meta-analysis

Cohort2026 · J Ovarian Res

Revisiting ESR in PCOS: an easily obtainable link to immune and metabolic dysregulation.

+5 more

About Cetrorelix

Competitive GnRH receptor antagonist; immediately blocks pituitary GnRH receptors; rapidly suppresses LH/FSH without initial flare effect; used for controlled hormonal suppression

Research Areas

HPG axis suppressionLH/FSH reductioncontrolled ovarian stimulation supporttestosterone management

About FSH

Binds FSH receptors on Sertoli cells in testes to support sperm maturation and inhibin B production. In women, binds granulosa cell FSH receptors to drive follicular growth and estradiol production.

Research Areas

spermatogenesisfertility supportfollicular developmentovarian stimulationHPG axis

Safety Profile

Information below reflects published research data only — not medical advice. Consult a qualified provider before use.

Cetrorelix

Absolute Contraindications

Pregnancy — contraindicatedLactation — contraindicated

Source: FDA label

Suggested Monitoring

Under clinical review

Being verified by our medical team before we display monitoring guidance for this peptide.

FSH

Absolute Contraindications

Under clinical review

Being verified by our medical team before we display contraindications for this peptide.

Suggested Monitoring

Under clinical review

Being verified by our medical team before we display monitoring guidance for this peptide.

Find Providers

Where to source these peptides

Providers offering

Cetrorelix

1 listed

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Providers offering

FSH

Browse directory →

PeptideBase lists providers for educational research purposes only. Always consult a qualified healthcare professional before obtaining or using any peptide.

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Educational research tools — not medical advice.