Neuropeptide that modulates sleep architecture by promoting delta-wave sleep patterns. Reduces stress hormones including ACTH and cortisol, and interacts with hypothalamic-pituitary pathways to support recovery and circadian regulation.

Selank is believed to modulate the expression of GABA-A receptor subunits and increase BDNF levels, contributing to its anxiolytic and neuroprotective profile. It appears to regulate serotonin transporter gene expression and influence dopaminergic signalling. Unlike classical anxiolytics, it does not appear to produce tolerance or physical dependence in animal models.