Is Cortexin FDA approved?

Cortexin is not evaluated or approved by the FDA. It is discussed for research and educational purposes only, not as medical guidance.

Is DSIP FDA approved?

DSIP is the subject of an unfavorable FDA advisory committee vote and not FDA approved. It is discussed for research and educational purposes only, not as medical guidance.

How is Cortexin administered in research settings?

In research settings, Cortexin is typically administered via the intramuscular route. PeptideBase does not provide dosing or administration instructions.

How is DSIP administered in research settings?

In research settings, DSIP is typically administered via the subcutaneous or intranasal routes. PeptideBase does not provide dosing or administration instructions.

Home›Research›Compare›Cortexin vs DSIP

Peptide Comparison

Cortexin vs DSIP

Name: Cortexin vs DSIP — Per-mg Price Comparison
Creator: PeptideBase
License: https://peptidebase.io/terms

Both are Neuro & Cognitive peptides.

Cortexin

Cortexin-10

CognitiveNot EvaluatedResearch Only

Half-life: Unknown

4 providers listed

Full Cortexin profile →

DSIP

Delta Sleep-Inducing Peptide

RecoveryAdvisory Vote: UnfavorableResearch Only

Half-life: 30–60 minutes

97 providers listed

Full DSIP profile →

Bottom line

DSIP is carried by more providers on PeptideBase (97 vs 4); otherwise the two are closely matched on the measures we track.

Quick Verdict

Cortexin

Half-life

Unknown

DSIP

Half-life

30–60 minutes

Which One Should You Choose?

Your goal	Better option
More provider options (4 vs 97)	DSIP

Research summary only — not medical advice. Consult a qualified provider before making any decisions.

Side-by-Side Comparison

Cortexin

DSIP

Mechanism Family

Neuro & Cognitive

Half-life

Unknown

30–60 minutes

FDA Status

not evaluated

advisory committee not recommended

Admin Routes

intramuscular

subcutaneous, intranasal

Availability

Research Only

Providers

4 listed

97 listed

FDA Update

—

Jul 2026

Avail. Notes

Russian polypeptide preparation from cattle cerebral cortex. Registered in Russia for neurological conditions. No FDA approval, no NDA or IND, not on any FDA list. Research chemical in US.

Endogenous neuropeptide discovered 1977. Studied for sleep disorders but no FDA approval, no NDA or IND. Not on 503A bulks list. Sold as research chemical only.

Research Evidence

Cortexin

Review · 1 key study · dated evidence base — most recent 2013

DSIP

Animal · 1 key study · dated evidence base — most recent 1979

Research Citations

Cortexin

Review2013 · Advances in gerontology

Neuroprotective effects of peptides bioregulators in people of various age

DSIP

Animal1979 · Neuroscience Letters

The delta-sleep inducing peptide (DSIP) increases duration of sleep in rats

About Cortexin

Polypeptide bioregulator from bovine cortex; modulates neurotransmitter activity; activates GABA and dopamine systems; reduces excitotoxicity; stimulates neuronal repair

Research Areas

neuroprotection and neuronal survival supportcognitive function improvement — documented in Russian clinical settingsantioxidant activity in CNS tissueEEG normalization and neurotrophic factor expression

About DSIP

Neuropeptide that modulates sleep architecture by promoting delta-wave sleep patterns. Reduces stress hormones including ACTH and cortisol, and interacts with hypothalamic-pituitary pathways to support recovery and circadian regulation.

Research Areas

sleep qualitystress reductionrecoverycortisol regulation

Safety Profile

Information below reflects published research data only — not medical advice. Consult a qualified provider before use.

Cortexin

Reported (Unverified — Pending Clinical Review)

bovine protein allergy

No established clinical contraindications

DSIP

No established clinical contraindications. This is an investigational compound with limited human data and has not been evaluated by the FDA for safety in this context. Consult a qualified clinician.

Price (per mg)

Cortexin

Not enough vendor pricing yet.

DSIP

$6.48/mg

$4.60 – $8.00 range

48 vendors

View price index →Find providers →

Find Providers

Where to source these peptides

Providers offering

Cortexin

4 listed

Browse directory →

Providers offering

DSIP

97 listed

Browse directory →

PeptideBase lists providers for educational research purposes only. Always consult a qualified healthcare professional before obtaining or using any peptide.

More Neuro & Cognitive Comparisons

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Educational research tools — not medical advice.

Cite this page

Data last updated August 26, 2026

Free to reference and republish with attribution to PeptideBase. Choose a format:

PeptideBase. (2026). Cortexin vs DSIP — Per-mg Price Comparison. Retrieved September 11, 2026, from https://peptidebase.io/peptides/compare/cortexin/dsip

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