EGF is not evaluated or approved by the FDA. It is discussed for research and educational purposes only, not as medical guidance.

Is FGF-1 FDA approved?

FGF-1 is not evaluated or approved by the FDA. It is discussed for research and educational purposes only, not as medical guidance.

How is EGF administered in research settings?

In research settings, EGF is typically administered via the topical, subcutaneous, or microneedling routes. PeptideBase does not provide dosing or administration instructions.

How is FGF-1 administered in research settings?

In research settings, FGF-1 is typically administered via the topical or subcutaneous routes. PeptideBase does not provide dosing or administration instructions.

Home›Research›Compare›EGF vs FGF-1

Peptide Comparison

EGF vs FGF-1

Q: What is the difference between EGF and FGF-1?

EGF: Binds EGFR (EGF receptor / ErbB1), activating RAS/MAPK and PI3K/Akt signaling cascades. FGF-1: Binds all four FGFR subtypes (broadest binding of FGF family). Activates MAPK and PI3K downstream pathways. Promotes fibroblast proliferation, angiogenesis, and hair follicle cycling into anagen phase.

Both are Skin & Cosmetic peptides.

EGF

Epidermal Growth Factor

Skin & JointNot EvaluatedResearch Only

No providers listed yet

Full EGF profile →

FGF-1

Fibroblast Growth Factor 1

Skin & JointNot EvaluatedResearch Only

No providers listed yet

Full FGF-1 profile →

Bottom line

FGF-1 carries stronger published evidence (RCT, 1 key studies) than EGF (Review, 2); both are research compounds.

Quick Verdict

EGF

FGF-1

Which One Should You Choose?

Your goal	Better option
Stronger clinical evidence	FGF-1

Research summary only — not medical advice. Consult a qualified provider before making any decisions.

Side-by-Side Comparison

EGF

FGF-1

Mechanism Family

Skin & Cosmetic

Half-life

—

FDA Status

not evaluated

Admin Routes

topical, subcutaneous, microneedling

topical, subcutaneous

Availability

Research Only

Providers

None listed

Research Evidence

EGF

Review · 2 key studies · most recent 2026

FGF-1

RCT · 1 key study · dated evidence base — most recent 2008

Research Citations

EGF

In vitro2026 · Gels

Development of Antiseptic and Epidermal Growth Factor Co-Loaded Thermoresponsive Composite Hydrogel for Wound…

Review2026 · Cell Tissue Bank

Determinants of extraction efficiency in human amniotic membrane processing: biological, mechanical, and bioc…

FGF-1

RCT2008 · Molecular Therapy

Therapeutic angiogenesis with intramuscular NV1FGF improves amputation-free survival in patients with critica…

About EGF

Binds EGFR (EGF receptor / ErbB1), activating RAS/MAPK and PI3K/Akt signaling cascades. Promotes keratinocyte and fibroblast proliferation, accelerates wound re-epithelialization, and stimulates collagen and hyaluronic acid production.

Research Areas

skin regenerationwound healingcollagen stimulationpost-procedure recovery

About FGF-1

Binds all four FGFR subtypes (broadest binding of FGF family). Activates MAPK and PI3K downstream pathways. Promotes fibroblast proliferation, angiogenesis, and hair follicle cycling into anagen phase.

Research Areas

wound healinghair growth supportskin repairangiogenesisfibroblast activation

Safety Profile

Information below reflects published research data only — not medical advice. Consult a qualified provider before use.

EGF

Absolute Contraindications

Under clinical review

Being verified by our medical team before we display contraindications for this peptide.

FGF-1

Absolute Contraindications

Under clinical review

Being verified by our medical team before we display contraindications for this peptide.

Find Providers

Where to source these peptides

Providers offering

EGF

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Providers offering

FGF-1

Browse directory →

PeptideBase lists providers for educational research purposes only. Always consult a qualified healthcare professional before obtaining or using any peptide.

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Educational research tools — not medical advice.