Educational use only — not medical advice
Research library
GHK-Cu benefits
From the PeptideBase research library. Educational only — not medical advice.
Studied effects
- collagen and elastin synthesis promotion via fibroblast activation
- skin wound healing and epidermal barrier function repair
- antioxidant and anti-inflammatory effects in skin tissue
- copper chelation supporting tissue remodeling and angiogenesis
Mechanism
GHK-Cu promotes the synthesis of collagen, elastin, glycosaminoglycans, and decorin, contributing to tissue remodelling and wound contraction. It modulates the activity of matrix metalloproteinases (MMPs) — stimulating wound-healing MMPs while suppressing those that degrade healthy tissue. Genomic analysis has identified GHK-Cu as a modulator of over 4,000 genes, including those governing antioxidant defences and anti-inflammatory pathways.