Educational use only — not medical advice
Research library
Ghrelin benefits
From the PeptideBase research library. Educational only — not medical advice.
Studied effects
- GH stimulation
- appetite stimulation
- metabolic regulation
- muscle preservation
Mechanism
Must be acylated at Ser3 (by GOAT enzyme) for GHSR-1a binding. Receptor activation in the pituitary stimulates GH release; hypothalamic action via NPY/AgRP neurons increases appetite and reduces energy expenditure.