Educational use only — not medical advice
Research library
IGF-DES benefits
From the PeptideBase research library. Educational only — not medical advice.
Studied effects
- muscle hypertrophy
- localized anabolism
- satellite cell activation
- tissue growth
Mechanism
N-terminal truncation eliminates IGFBP binding, leaving nearly all circulating IGF-DES unbound and active. Results in substantially higher tissue IGF-1R activation versus native IGF-1 at equivalent doses. Activates PI3K/Akt/mTOR for muscle hypertrophy and satellite cell proliferation.