sexual_healthLow Risk

Kisspeptin-54

Also known as: KP-54, Metastin, KISS1 54-mer

Half-life:: ~29 minutes

Administration Routes

subcutaneous injectionintravenous

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Mechanism of Action

Full-length kisspeptin (54 amino acids); binds KISS1R on GnRH neurons with higher receptor occupancy and longer duration than KP-10; induces more sustained GnRH/LH pulses

The full-length kisspeptin with a longer duration of action than Kisspeptin-10 (KP-10/ID 47). Produces more sustained HPG axis stimulation; studied for infertility treatment and hypogonadism.

Primary Research Areas

sustained LH/FSH stimulation
testosterone support
fertility induction
reproductive function

Risk Profile

Low Risk

Generally considered lower risk in research contexts. Consult a healthcare professional before use.

Regulatory Status

Research OnlyInvestigational

No FDA approval. Longer-acting kisspeptin isoform under Phase 1/2 investigation for reproductive disorders in EU and US. No NDA filed. Research peptide only.

Regulatory status reflects publicly available information and may change. This is not legal or medical advice.

Where to Find Kisspeptin-54

No active associated providers listed yet.