Educational use only — not medical advice
Research library
Melanotan II benefits
From the PeptideBase research library. Educational only — not medical advice.
Studied effects
- central MC4R-mediated sexual arousal and erectile function
- skin tanning via MC1R melanogenesis activation
- appetite suppression (MC4R hypothalamic pathway)
- significant side effect profile — nausea, flushing, pigmentation (vs cleaner successor PT-141)
Mechanism
Synthetic melanocortin receptor agonist (MC1R-MC5R); activates MC4R for erectile function/libido; MC1R for melanogenesis; MC3R for appetite suppression