Home›Research›Compare›Alpha-MSH vs GLP-2
Peptide Comparison
Alpha-MSH vs GLP-2
Both are Recovery peptides.
Alpha-MSH
Alpha-Melanocyte Stimulating Hormone
Half-life: ~3-5 minutes (plasma)
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Quick Verdict
Alpha-MSH
Risk
Half-life
~3-5 minutes (plasma)
GLP-2
Risk
Half-life
—
Side-by-Side Comparison
About Alpha-MSH
Melanocortin peptide; activates MC1R (pigmentation/anti-inflammatory), MC3R (energy balance), MC4R (appetite); suppresses NF-κB and pro-inflammatory cytokines
The parent melanocortin peptide from which KPV is derived. Regulates inflammation, appetite, and body temperature through MC receptor subtypes. Studied for inflammatory and autoimmune conditions.
Research Areas
About GLP-2
Binds GLP-2 receptor on intestinal enteroendocrine cells. Promotes enterocyte proliferation and reduces apoptosis, increasing villus height and crypt depth. Strengthens tight junctions and reduces intestinal permeability.
A 33-amino acid intestinal peptide co-secreted with GLP-1 from gut L-cells after eating. A potent intestinal trophic factor promoting gut lining integrity, villus growth, and reduced intestinal permeability. Studied for IBD, leaky gut, and gut repair.
Research Areas
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