What is the difference between Angiotensin (1-7) and Retinalamin?

Angiotensin (1-7): Binds Mas receptor (MasR), activating nitric oxide synthase and reducing oxidative stress. Opposes TGF-β and angiotensin II signaling to reduce fibrosis. Retinalamin: Polypeptide bioregulator from bovine retina; normalizes retinal pigment epithelial and photoreceptor cell function; reduces oxidative damage in retinal tissue

Is Angiotensin (1-7) FDA approved?

Angiotensin (1-7) is investigational and not FDA approved. It is discussed for research and educational purposes only, not as medical guidance.

Is Retinalamin FDA approved?

Retinalamin is not evaluated or approved by the FDA. It is discussed for research and educational purposes only, not as medical guidance.

How is Angiotensin (1-7) administered in research settings?

In research settings, Angiotensin (1-7) is typically administered via the subcutaneous or intravenous routes. PeptideBase does not provide dosing or administration instructions.

How is Retinalamin administered in research settings?

In research settings, Retinalamin is typically administered via the parabulbar injection or intramuscular routes. PeptideBase does not provide dosing or administration instructions.

Home›Research›Compare›Angiotensin (1-7) vs Retinalamin

Peptide Comparison

Angiotensin (1-7) vs Retinalamin

Both are Longevity & Cellular peptides.

Angiotensin (1-7)

Ang-(1-7)

LongevityInvestigationalResearch Only

Half-life: ~9–10 sec (rat)

No providers listed yet

Full Angiotensin (1-7) profile →

Retinalamin

Retinal bioregulator

LongevityNot EvaluatedResearch Only

Half-life: Unknown

1 providers listed

Full Retinalamin profile →

Bottom line

Angiotensin (1-7) carries stronger published evidence (RCT, 9 key studies) than Retinalamin (Review, 2); both are research compounds.

Quick Verdict

Angiotensin (1-7)

Half-life

~9–10 sec (rat)

Retinalamin

Half-life

Unknown

Which One Should You Choose?

Your goal	Better option
Stronger clinical evidence	Angiotensin (1-7)
Further along in FDA review	Angiotensin (1-7)
More provider options (0 vs 1)	Retinalamin

Research summary only — not medical advice. Consult a qualified provider before making any decisions.

Side-by-Side Comparison

Angiotensin (1-7)

Retinalamin

Mechanism Family

Longevity & Cellular

Half-life

~9–10 sec (rat)

Unknown

FDA Status

investigational

not evaluated

Admin Routes

subcutaneous, intravenous

parabulbar injection, intramuscular

Availability

Research Only

Providers

None listed

1 listed

Avail. Notes

—

Russian retinal peptide bioregulator (Khavinson Institute). Used in Russia for age-related retinal degeneration. Not FDA-approved. Not available in US except as research chemical.

Research Evidence

Angiotensin (1-7)

RCT · 9 key studies · most recent 2026

Retinalamin

Review · 2 key studies · most recent 2022

Research Citations

Angiotensin (1-7)

RCT2026 · J Alzheimers Dis

Association between renin angiotensin system and cognitive outcomes over 15 years: The Look AHEAD study.

RCT2024 · Annals of Intensive Care

Angiotensin-(1-7) improves oxygenation in mechanically ventilated COVID-19 patients: a randomized phase 1-2 s…

Case series2026 · Res Sq

Perioperative Angiotensin-(1-7) for Postoperative Cognitive Vulnerability Following Coronary Artery Bypass Su…

Animal2026 · Metabolites

The Effect of Angiotensin (1-7) on Serum Metabolomics in Obese Type 2 Diabetic Mice.

+5 more

Retinalamin

Review2022 · International Journal of Molecular Sciences

Bioavailability and Biological Activities of Food-Derived Di- and Tripeptides: In Silico and In Vitro Studies

Review2022 · International Journal of Molecular Sciences

Peptide Regulation of Gene Expression and Protein Synthesis in Bronchial Epithelium

About Angiotensin (1-7)

Binds Mas receptor (MasR), activating nitric oxide synthase and reducing oxidative stress. Opposes TGF-β and angiotensin II signaling to reduce fibrosis. Enhances insulin sensitivity and provides cardiovascular protection.

Research Areas

cardiovascular protectionanti-fibroticvasodilationinsulin sensitivitykidney protection

About Retinalamin

Polypeptide bioregulator from bovine retina; normalizes retinal pigment epithelial and photoreceptor cell function; reduces oxidative damage in retinal tissue

Research Areas

retinal cell protectionvisual function restorationmacular degeneration supportanti-aging (eyes)

Safety Profile

Information below reflects published research data only — not medical advice. Consult a qualified provider before use.

Angiotensin (1-7)

No established clinical contraindications. This is an investigational compound with limited human data and has not been evaluated by the FDA for safety in this context. Consult a qualified clinician.

Retinalamin

Reported (Unverified — Pending Clinical Review)

bovine protein allergy

No established clinical contraindications

Find Providers

Where to source these peptides

Providers offering

Angiotensin (1-7)

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Providers offering

Retinalamin

1 listed

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PeptideBase lists providers for educational research purposes only. Always consult a qualified healthcare professional before obtaining or using any peptide.

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Educational research tools — not medical advice.