Cerluten vs Klotho

CNS-targeted peptide complex that modulates neuronal gene expression. Shown in Russian clinical studies to improve memory consolidation, attention, and protect against neurodegeneration.

A short peptide bioregulator derived from brain and CNS tissue, developed by the Khavinson Institute. Studied for cognitive support, neuroprotection, and mitigation of age-related cognitive decline.

Acts as a co-receptor for FGF23, regulating phosphate and vitamin D metabolism. As a circulating hormone, inhibits insulin/IGF-1 signaling to extend lifespan, activates Nrf2 antioxidant pathways, and suppresses TGF-β fibrotic signaling.

A fragment of the anti-aging Klotho protein that circulates as a hormone after ectodomain shedding. Naturally declines with age. Low Klotho levels are associated with accelerated aging, cognitive decline, cardiovascular disease, and reduced lifespan in animal models.