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Skin & JointLow Risk

Palmitoyl Tripeptide-1

Also known as: Pal-GHK, Biopeptide CL, SYN-COLL

Half-life:
N/A (topical)

Administration Routes

topical
PeptideBase provides educational research tools and provider discovery. It does not provide medical advice, diagnosis, treatment, prescribing guidance, or dosing instructions. Consult a qualified healthcare professional before making health decisions.

Mechanism of Action

Palmitoylated GHK fragment; stimulates collagen I, III, and IV synthesis via TGF-β pathway; increases fibronectin and hyaluronic acid production

A fatty acid-conjugated tripeptide that stimulates collagen production in dermal fibroblasts. Improves skin firmness and reduces wrinkle depth with topical use.

Primary Research Areas

  • collagen synthesis
  • skin firmness
  • anti-aging
  • wound healing

Risk Profile

Low Risk

Generally considered lower risk in research contexts. Consult a healthcare professional before use.

Regulatory Status

Research OnlyNot Evaluated by FDA

Cosmetic peptide (Pal-GHK, palmitoyl tripeptide-1). Palmitate conjugate of GHK tripeptide. Not regulated as a drug by FDA. No NDA or IND. Cosmetic anti-aging ingredient only.

Regulatory status reflects publicly available information and may change. This is not legal or medical advice.

Where to Find Palmitoyl Tripeptide-1