About SYN-AKE
Reversibly antagonizes nicotinic acetylcholine receptors (nAChR) at neuromuscular junctions in facial skin, reducing involuntary muscle microcontractions. Effect is topical, localized, and fully reversible.
A synthetic tripeptide that mimics the effect of waglerin-1 from temple viper venom by temporarily inhibiting muscle microcontraction at dermal neuromuscular junctions. Used as a topical non-invasive alternative to botulinum toxin for expression line reduction.
Research Areas
Regulatory & Evidence
Risk Profile
Generally considered lower risk in research contexts. Risk profile varies by individual — review contraindications before use.
Regulatory Status
- Availability Status
- Research Only
Regulatory status reflects publicly available information and may change. This is not legal or medical advice.
Safety Notes
Generally considered lower risk in research contexts. Individual response varies — review all considerations before use.
Reported contraindications & considerations
Consult a qualified healthcare professional before making any health decisions. This information is educational only and does not constitute medical advice.
Where to Find SYN-AKE
Coverage expanding
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Frequently Asked Questions — SYN-AKE
A synthetic tripeptide that mimics the effect of waglerin-1 from temple viper venom by temporarily inhibiting muscle microcontraction at dermal neuromuscular junctions. Used as a topical non-invasive alternative to botulinum toxin for expression line reduction.
wrinkle reduction, expression line softening, muscle relaxation, anti-aging.