EGF vs SYN-AKE

Binds EGFR (EGF receptor / ErbB1), activating RAS/MAPK and PI3K/Akt signaling cascades. Promotes keratinocyte and fibroblast proliferation, accelerates wound re-epithelialization, and stimulates collagen and hyaluronic acid production.

A 53-amino acid protein that potently stimulates cell proliferation and differentiation in epithelial and fibroblast cells. Widely used in aesthetic medicine for wound healing, skin regeneration, and post-procedure recovery. One of the most established growth factors in cosmetic dermatology.

Reversibly antagonizes nicotinic acetylcholine receptors (nAChR) at neuromuscular junctions in facial skin, reducing involuntary muscle microcontractions. Effect is topical, localized, and fully reversible.

A synthetic tripeptide that mimics the effect of waglerin-1 from temple viper venom by temporarily inhibiting muscle microcontraction at dermal neuromuscular junctions. Used as a topical non-invasive alternative to botulinum toxin for expression line reduction.