Larazotide
Price and cost-per-mg comparison
Larazotide acetate (AT-1001) is a synthetic octapeptide zonulin antagonist that reduces intestinal permeability by blocking zonulin-mediated disassembly of intestinal epithelial tight junctions, studied as an adjunctive treatment to reduce symptom burden in celiac disease patients during inadvertent or deliberate gluten exposure. By inhibiting zonulin receptor signaling, larazotide prevents the disruption of tight junction proteins — including occludin and claudins — that would otherwise permit immunogenic gluten peptides to traverse the epithelial barrier and trigger the CD4+ T-cell-mediated mucosal injury characteristic of active celiac disease. A Phase 2 randomized, double-blind trial published in The American Journal of Gastroenterology demonstrated that larazotide acetate reduced activation of celiac disease during gluten challenge; however, the Phase 3 trial published in Gastroenterology, designed to evaluate larazotide for persistent symptoms in celiac disease patients already following a gluten-free diet, did not meet its primary endpoint. Larazotide has not received FDA approval; no NDA has been filed following the Phase 3 outcome, and it remains an investigational compound with no approved indication.
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Filter by vial size and quantity — the figures and table follow.
| Vendor | Size | Price | Cost per mg▲ | COA | Source | Availability | Actions |
|---|---|---|---|---|---|---|---|
Other sizessingle vials, one listing each2 listingsmedian $10.60 / mg | |||||||
US Larazotide 5mg | 5 mg vial | $50.00 | $10.00 | — | Vendor feed · 2 mo ago | — | View ↗ |
US Larazotide Acetate (AT-1001, 10mg) | 10 mg vial | $111.99 | $11.20 | — | Vendor feed · 2 wk ago | In stock | View ↗ |
Not comparableno resolvable mg — shown, not ranked2 listings | |||||||
US BPC/KPV/Larazotide Research Blend | blend | $169.00 | — | Vendor feed · 2 wk ago | In stock | View ↗ | |
CA Larazotide — 1mg × 30 Caps | Zonulin Antagonist | capsules | $71.99 | — | Vendor feed · 2 wk ago | In stock | View ↗ | |
— in COA: no certificate on file for this vendor— in availability: stock not read at the last checkPrices as scraped; foreign prices converted to USD
When Larazotide prices moved
0 days in the last 120 on which a feed run read comparable Larazotide prices from 3 or more vendors. Each point is the median $/mg across every comparable listing read that day, sized by how many vendors were read. A log of run days, not a continuous series.
How these prices are computed
The short version. The methodology page has the rest.
Source
Prices are read from each vendor's own store feed or product markup (Vendor feed). Every row says which source it came from and when it was read. Prices parsed from page text are not in this index.
$/mg
Listed price ÷ stated milligrams, converted to USD. Packs are priced on total milligrams. Listings sold per kit, per ml, as capsules or sprays, as blends, or without a stated mass are shown but not ranked.
Population
Active online research vendors only. Clinic, pharmacy and telehealth prices are excluded. Medians and the p25–p75 band are computed over comparable listings, one row per vendor product and size.
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Educational research tools — not medical advice.