Triptorelin
Price and cost-per-mg comparison
Triptorelin is a synthetic decapeptide GnRH agonist with a longer half-life than endogenous GnRH, used clinically to produce controlled hormonal suppression of the reproductive axis via receptor downregulation. Unlike the brief stimulatory effect of native GnRH, continuous or depot administration of triptorelin paradoxically desensitizes pituitary GnRH receptors, producing sustained suppression of LH, FSH, and sex hormone levels through a process known as medical castration. Clinical trials have established triptorelin efficacy for androgen deprivation therapy in prostate cancer, treatment of central precocious puberty, and hormonal management of endometriosis and uterine fibroids. Triptorelin is an FDA-approved prescription medication (Trelstar) available in depot formulations; it requires specialist-supervised monitoring due to an initial hormonal flare on commencement and the significant physiological effects of prolonged sex hormone suppression. Triptorelin for HPTA restart (PCT context) Outside its approved indications, triptorelin has been discussed in post-cycle therapy (PCT) and testosterone replacement therapy (TRT) restart contexts. The rationale is mechanistic: a single low dose of triptorelin triggers a brief, intense LH and FSH pulse before inducing pituitary downregulation — this initial agonist surge may be sufficient to re-sensitise a suppressed hypothalamic-pituitary-gonadal (HPG) axis following prolonged androgen administration that has blunted endogenous LH/FSH production. Some research and anecdotal literature describes single-dose triptorelin protocols as an HPTA restart approach, with the goal of re-initiating endogenous testosterone production. This use is not FDA-approved, not evaluated in randomised controlled trials for this indication, and not a standard of care in any guideline. It represents an off-label research and community-practice area. Triptorelin's mechanism — producing sustained hormonal suppression — means that incorrect dosing or repeated administration would achieve the opposite of the desired restart effect; this context requires qualified clinical supervision. PeptideBase does not endorse off-label use; this is informational context about how the compound is discussed in research and clinical community settings.
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| Vendor | Size | Price | Cost per mg▲ | COA | Source | Availability | Actions |
|---|---|---|---|---|---|---|---|
2 mgsingle vials2 listingsmedian $20.30 / mg | |||||||
UK Triptorelin For Lab Research | 2 mg vial | $27.20listed GBP 20.00 | $13.60Lowest | — | Vendor feed · 2 wk ago | Out of stock | View ↗ |
US Triptorelin – 2MG | 2 mg vial | $54.00 | $27.00 | Vendor feed · 2 wk ago | In stock | View ↗ | |
Not comparableno resolvable mg — shown, not ranked1 listing | |||||||
US Triptorelin Peptide Vial | mass not stated | $19.07 | — | Vendor feed · 2 wk ago | In stock | View ↗ | |
— in COA: no certificate on file for this vendor— in availability: stock not read at the last checkPrices as scraped; foreign prices converted to USD
When Triptorelin prices moved
0 days in the last 120 on which a feed run read comparable Triptorelin prices from 3 or more vendors. Each point is the median $/mg across every comparable listing read that day, sized by how many vendors were read. A log of run days, not a continuous series.
How these prices are computed
The short version. The methodology page has the rest.
Source
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$/mg
Listed price ÷ stated milligrams, converted to USD. Packs are priced on total milligrams. Listings sold per kit, per ml, as capsules or sprays, as blends, or without a stated mass are shown but not ranked.
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Active online research vendors only. Clinic, pharmacy and telehealth prices are excluded. Medians and the p25–p75 band are computed over comparable listings, one row per vendor product and size.
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