Home›Research›Compare›CGRP vs Teduglutide
Peptide ComparisonCGRP vs Teduglutide
Both are Tissue Repair peptides.
CGRP
Calcitonin Gene-Related Peptide
Half-life: ~3.6 min / ~13.6 min (biphasic; sheep)
2 providers listed
Teduglutide
Gattex
Half-life: ~2 hours
No providers listed yet
Teduglutide is FDA-approved, while CGRP is not evaluated — the clearest structural difference between them.
CGRP
Half-life
~3.6 min / ~13.6 min (biphasic; sheep)
Teduglutide
Half-life
~2 hours
| Your goal | Better option |
|---|---|
| Stronger clinical evidence | CGRP |
| Further along in FDA review | Teduglutide |
| Less frequent dosing (longer half-life) | Teduglutide |
| More provider options (2 vs 0) | CGRP |
Research summary only — not medical advice. Consult a qualified provider before making any decisions.
CGRP
Teduglutide
CGRP
Efficacy and tolerability of erenumab in patients with episodic migraine in whom two-to-four previous prevent…
A Controlled Trial of Erenumab for Episodic Migraine
Three-year real-world effectiveness, treatment persistence, and planned discontinuation of anti-calcitonin ge…
Functional role of Nav1.8 channels in action potentials of mouse CGRP-lineage dorsal root ganglion neurons.
+6 more
Teduglutide
From childhood to adulthood in chronic intestinal failure: A nationwide study.
PERCC1-associated enteropathy: Diagnostic challenges and enteral autonomy achieved with teduglutide.
Growth trajectories of children with short bowel syndrome during the first year of teduglutide treatment.
Real-world experience of teduglutide for the treatment of short bowel syndrome-associated intestinal failure.
+4 more
About CGRP
Binds CLR/RAMP1 receptor complex. Causes vasodilation via cAMP/PKA/nitric oxide pathway. Modulates nociceptive signaling in the trigeminal system. Promotes bone healing and has anti-inflammatory effects in peripheral tissues.
About Teduglutide
GLP-2 receptor agonist; stimulates intestinal epithelial proliferation and reduces apoptosis; increases intestinal blood flow and inhibits gastric motility
Information below reflects published research data only — not medical advice. Consult a qualified provider before use.
CGRP
No established clinical contraindications. This is an investigational compound with limited human data and has not been evaluated by the FDA for safety in this context. Consult a qualified clinician.
Under clinical review
Being verified by our medical team before we display monitoring guidance for this peptide.
Teduglutide
No established clinical contraindications
Under clinical review
Being verified by our medical team before we display monitoring guidance for this peptide.
Where to source these peptides
PeptideBase lists providers for educational research purposes only. Always consult a qualified healthcare professional before obtaining or using any peptide.
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