Home›Research›Compare›CGRP vs LL-37
Peptide ComparisonCGRP vs LL-37
Both are Tissue Repair peptides.
CGRP
Calcitonin Gene-Related Peptide
Half-life: ~3.6 min / ~13.6 min (biphasic; sheep)
2 providers listed
CGRP is FDA-approved, while LL-37 is nomination withdrawn — the clearest structural difference between them.
CGRP
Evidence
Half-life
~3.6 min / ~13.6 min (biphasic; sheep)
LL-37
Evidence
Half-life
~30 minutes
| Your goal | Better option |
|---|---|
| Stronger clinical evidence | CGRP |
| Further along in FDA review | CGRP |
| Less frequent dosing (longer half-life) | LL-37 |
| More provider options (2 vs 38) | LL-37 |
Research summary only — not medical advice. Consult a qualified provider before making any decisions.
CGRP
LL-37
CGRP
Efficacy and tolerability of erenumab in patients with episodic migraine in whom two-to-four previous prevent…
A Controlled Trial of Erenumab for Episodic Migraine
Three-year real-world effectiveness, treatment persistence, and planned discontinuation of anti-calcitonin ge…
Astrocyte-Targeted Biomarkers for Calcitonin Gene-Related Peptide-Related Neurovascular Disorders: Insights f…
+10 more
LL-37
Immunomodulatory effects of synthetic antimicrobial peptides on LPS-induced inflammatory responses in THP-1 m…
The Role of Vitamin D in Modulating the Innate Immune Response in Children with Vesicoureteral Reflux.
Antimicrobial peptoids pass rapidly through bacterial membranes and flocculate ribosomes and DNA: A single-ce…
Antimicrobial peptoids pass rapidly through bacterial membranes and flocculate ribosomes and DNA: A single-ce…
+15 more
About CGRP
Binds CLR/RAMP1 receptor complex. Causes vasodilation via cAMP/PKA/nitric oxide pathway. Modulates nociceptive signaling in the trigeminal system. Promotes bone healing and has anti-inflammatory effects in peripheral tissues.
About LL-37
Human cathelicidin antimicrobial peptide; disrupts bacterial membranes and modulates innate immune response via TLR signaling
Information below reflects published research data only — not medical advice. Consult a qualified provider before use.
CGRP
No structured contraindication profile is available for this compound yet. This compound is FDA-approved — consult the official prescribing information or a qualified clinician.
Under clinical review
Being verified by our medical team before we display monitoring guidance for this peptide.
LL-37
No established clinical contraindications
CGRP
Not enough vendor pricing yet.
LL-37
Where to source these peptides
PeptideBase lists providers for educational research purposes only. Always consult a qualified healthcare professional before obtaining or using any peptide.
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Cite this page
Data last updated July 20, 2026
Free to reference and republish with attribution to PeptideBase. Choose a format:
PeptideBase. (2026). CGRP vs LL-37 — Per-mg Price Comparison. Retrieved July 22, 2026, from https://peptidebase.io/peptides/compare/cgrp/ll-37