What is the difference between CJC-1295 (without DAC) and Hexarelin?

CJC-1295 (without DAC): CJC-1295 without DAC (Mod GRF 1-29) is a short-acting GHRH analog that binds and activates pituitary GHRH receptors to stimulate brief, pulsatile growth hormone release. Hexarelin: Potent synthetic GHRP; strongest GH secretagogue in its class; also activates CD36 scavenger receptor for cardioprotective effects

Is Hexarelin FDA approved?

Hexarelin is not evaluated or approved by the FDA. It is discussed for research and educational purposes only, not as medical guidance.

How is CJC-1295 (without DAC) administered in research settings?

In research settings, CJC-1295 (without DAC) is typically administered via the subcutaneous route. PeptideBase does not provide dosing or administration instructions.

How is Hexarelin administered in research settings?

In research settings, Hexarelin is typically administered via the subcutaneous route. PeptideBase does not provide dosing or administration instructions.

Home›Research›Compare›CJC-1295 (without DAC) vs Hexarelin

Peptide Comparison

CJC-1295 (without DAC) vs Hexarelin

Name: CJC-1295 (without DAC) vs Hexarelin — Per-mg Price Comparison
Creator: PeptideBase
License: https://peptidebase.io/terms

Both are GH / IGF Axis peptides.

CJC-1295 (without DAC)

CJC 1295

Fat LossResearch Only

Half-life: ~30 minutes

454 providers listed

Full CJC-1295 (without DAC) profile →

Hexarelin

Examorelin

PerformanceNot EvaluatedResearch Only

Half-life: ~30-60 minutes

23 providers listed

Full Hexarelin profile →

Bottom line

CJC-1295 (without DAC) is carried by more providers on PeptideBase (454 vs 23); otherwise the two are closely matched on the measures we track.

Quick Verdict

CJC-1295 (without DAC)

Half-life

~30 minutes

Hexarelin

Half-life

~30-60 minutes

Which One Should You Choose?

Your goal	Better option
Stronger clinical evidence	CJC-1295 (without DAC)
More provider options (454 vs 23)	CJC-1295 (without DAC)

Research summary only — not medical advice. Consult a qualified provider before making any decisions.

Side-by-Side Comparison

CJC-1295 (without DAC)

Hexarelin

Mechanism Family

GH / IGF Axis

Half-life

~30 minutes

~30-60 minutes

FDA Status

nomination withdrawn

not evaluated

Admin Routes

subcutaneous

Availability

Research Only

Providers

454 listed

23 listed

Avail. Notes

GHRH analog — the truncated 1-29 form (Mod GRF 1-29), WITHOUT the Drug Affinity Complex (DAC). No FDA approval; not on the FDA 503A bulks list. WADA prohibited (S2) as a growth-hormone-releasing factor. Sold as a research chemical only.

Potent hexapeptide GH secretagogue. No FDA approval anywhere. Not on FDA Category 1 or Category 2 list. WADA prohibited. More potent GH pulse than GHRP-6. Research use only.

Research Evidence

CJC-1295 (without DAC)

RCT · 3 key studies · most recent 2026

Hexarelin

RCT · 1 key study · dated evidence base — most recent 2001

Research Citations

CJC-1295 (without DAC)

RCT1997 · Journal of Clinical Endocrinology and Metabolism

Endocrine and metabolic effects of long-term administration of [Nle27]growth hormone-releasing hormone-(1-29)…

RCT1997 · Journal of Clinical Endocrinology and Metabolism

Effects of [norleucine27]growth hormone-releasing hormone (GHRH) (1-29)-NH2 administration on the immune syst…

Review2026 · JBJS Rev

Injectable Peptides in Sports Medicine: A Structured Narrative Review of Evidence, Safety, and Antidoping Imp…

Hexarelin

RCT2001 · Journal of Clinical Endocrinology and Metabolism

Endocrine activities of ghrelin, a natural growth hormone secretagogue (GHS), in humans: comparison and inter…

About CJC-1295 (without DAC)

CJC-1295 without DAC (Mod GRF 1-29) is a short-acting GHRH analog that binds and activates pituitary GHRH receptors to stimulate brief, pulsatile growth hormone release. Lacking the Drug Affinity Complex, it is not albumin-bound and clears within roughly half an hour, producing discrete GH pulses rather than the sustained elevation of the DAC form.

Research Areas

GH and IGF-1 elevationsustained GHRH receptor agonismbody composition supportrecovery enhancementGH axis restoration

About Hexarelin

Potent synthetic GHRP; strongest GH secretagogue in its class; also activates CD36 scavenger receptor for cardioprotective effects

Research Areas

potent GH secretion via GHS-R1a agonismcardiac tissue activity via CD36 receptor pathwaysmuscle recovery and lean mass supportreceptor desensitization with repeated use — cycling protocols studied

Safety Profile

Information below reflects published research data only — not medical advice. Consult a qualified provider before use.

CJC-1295 (without DAC)

Warnings & Cautions

Active malignancy — caution (GH/IGF-1 is mitogenic)Pregnancy — cautionKnown hypersensitivityGlucose intolerance / insulin resistance

Class-based (investigational)

Suggested Monitoring

IGF-1Fasting glucoseHbA1cInsulin

Research protocols routinely measure IGF-1 to track GH axis activity before and during use. Fasting glucose and insulin are monitored because GH elevation can reduce insulin sensitivity over time.

Regulatory Notes

global — WADA

This compound falls under WADA Prohibited List category S2 (Peptide Hormones, Growth Factors, Related Substances and Mimetics), prohibited at all times for competing athletes.

source

Hexarelin

Absolute Contraindications

Under clinical review

Being verified by our medical team before we display contraindications for this peptide.

Used Together?

CJC-1295 (without DAC)

Ipamorelin
Research suggests Ipamorelin and CJC-1295 may produce enhanced growth hormone release effects when combined. CJC-1295 provides sustained GHRH receptor stimulation while Ipamorelin provides pulsatile ghrelin receptor stimulation — complementary pathways studied in GH secretion research.
GLP-1 agonists
Research notes metabolic pathway overlap between growth hormone-releasing peptides and GLP-1 agonists. Both compound classes influence metabolic signaling; limited research has studied their combined effects. Consult your prescriber before combining.

Price (per mg)

CJC-1295 (without DAC)

$8.20/mg

$7.07 – $11.29 range

42 vendors

View price index →Find providers →

Hexarelin

$9.46/mg

$8.09 – $11.40 range

19 vendors

View price index →Find providers →

Find Providers

Where to source these peptides

Providers offering

CJC-1295 (without DAC)

454 listed

Browse directory →

Providers offering

Hexarelin

23 listed

Browse directory →

PeptideBase lists providers for educational research purposes only. Always consult a qualified healthcare professional before obtaining or using any peptide.

More GH / IGF Axis Comparisons

Browse all peptides →

Educational research tools — not medical advice.

Cite this page

Data last updated August 26, 2026

Free to reference and republish with attribution to PeptideBase. Choose a format:

PeptideBase. (2026). CJC-1295 (without DAC) vs Hexarelin — Per-mg Price Comparison. Retrieved August 26, 2026, from https://peptidebase.io/peptides/compare/cjc-1295/hexarelin

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