Is FGF-1 FDA approved?

FGF-1 is not evaluated or approved by the FDA. It is discussed for research and educational purposes only, not as medical guidance.

Is KGF-1 FDA approved?

KGF-1 is not evaluated or approved by the FDA. It is discussed for research and educational purposes only, not as medical guidance.

How is FGF-1 administered in research settings?

In research settings, FGF-1 is typically administered via the topical or subcutaneous routes. PeptideBase does not provide dosing or administration instructions.

How is KGF-1 administered in research settings?

In research settings, KGF-1 is typically administered via the subcutaneous or topical routes. PeptideBase does not provide dosing or administration instructions.

Home›Research›Compare›FGF-1 vs KGF-1

Peptide Comparison

FGF-1 vs KGF-1

Q: What is the difference between FGF-1 and KGF-1?

FGF-1: Binds all four FGFR subtypes (broadest binding of FGF family). Activates MAPK and PI3K downstream pathways. Promotes fibroblast proliferation, angiogenesis, and hair follicle cycling into anagen phase. KGF-1: Binds FGFR2b (the KGF receptor), which is exclusively expressed on epithelial cells — providing tissue-specific action without mesenchymal effects.

Both are Skin & Cosmetic peptides.

FGF-1

Fibroblast Growth Factor 1

Skin & JointNot EvaluatedResearch Only

No providers listed yet

Full FGF-1 profile →

KGF-1

FGF-7

Skin & JointNot EvaluatedResearch Only

No providers listed yet

Full KGF-1 profile →

Bottom line

FGF-1 and KGF-1 are closely matched on the structured measures we track — availability, evidence, and regulatory status are similar.

Quick Verdict

FGF-1

KGF-1

Side-by-Side Comparison

FGF-1

KGF-1

Mechanism Family

Skin & Cosmetic

Half-life

—

FDA Status

not evaluated

Admin Routes

topical, subcutaneous

subcutaneous, topical

Availability

Research Only

Providers

None listed

Avail. Notes

—

Native KGF-1/FGF-7 is not an FDA-approved substance. The approved product is palifermin (Kepivance, BLA 125103, approved 2004-12-15), which the label describes as differing from endogenous human KGF in that the first 23 N-terminal amino acids have been deleted to improve protein stability. The 2004-12-15 date previously carried on this record was palifermin's approval date.

Research Evidence

FGF-1

RCT · 1 key study · dated evidence base — most recent 2008

KGF-1

RCT · 1 key study · dated evidence base — most recent 2004

Research Citations

FGF-1

RCT2008 · Molecular Therapy

Therapeutic angiogenesis with intramuscular NV1FGF improves amputation-free survival in patients with critica…

KGF-1

RCT2004 · New England Journal of Medicine

Palifermin for oral mucositis after intensive therapy for hematologic cancers

About FGF-1

Binds all four FGFR subtypes (broadest binding of FGF family). Activates MAPK and PI3K downstream pathways. Promotes fibroblast proliferation, angiogenesis, and hair follicle cycling into anagen phase.

Research Areas

wound healinghair growth supportskin repairangiogenesisfibroblast activation

About KGF-1

Binds FGFR2b (the KGF receptor), which is exclusively expressed on epithelial cells — providing tissue-specific action without mesenchymal effects. Activates RAS/MAPK and PI3K/Akt to promote keratinocyte proliferation and migration. Extends the anagen phase of the hair growth cycle.

Research Areas

wound healinghair growthkeratinocyte proliferationmucosal repairepithelial protection

Safety Profile

Information below reflects published research data only — not medical advice. Consult a qualified provider before use.

FGF-1

Absolute Contraindications

Under clinical review

Being verified by our medical team before we display contraindications for this peptide.

KGF-1

Absolute Contraindications

Under clinical review

Being verified by our medical team before we display contraindications for this peptide.

Suggested Monitoring

Under clinical review

Being verified by our medical team before we display monitoring guidance for this peptide.

Find Providers

Where to source these peptides

Providers offering

FGF-1

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Providers offering

KGF-1

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PeptideBase lists providers for educational research purposes only. Always consult a qualified healthcare professional before obtaining or using any peptide.

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Educational research tools — not medical advice.