Home›Research›Compare›Foxo4-DRI vs Humanin
Peptide ComparisonFoxo4-DRI vs Humanin
Both are Longevity & Cellular peptides.
Foxo4-DRI
Foxo4-D-Retro-Inverso
Half-life: Unknown
14 providers listed
Humanin
HN
Half-life: ~2-4 hours
10 providers listed
Foxo4-DRI is carried by more providers on PeptideBase (14 vs 10); otherwise the two are closely matched on the measures we track.
Foxo4-DRI
Half-life
Unknown
Humanin
Half-life
~2-4 hours
| Your goal | Better option |
|---|---|
| Lower typical price per mg | Humanin |
| More provider options (14 vs 10) | Foxo4-DRI |
Research summary only — not medical advice. Consult a qualified provider before making any decisions.
Foxo4-DRI
Humanin
Foxo4-DRI
Rational design of a peptide inducing selective apoptosis of p53-high senescent cells by targeting the FOXO4-…
Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging
Targeting the FOXO4-p53 axis by retro-inverso peptide senolytic agents: a pharmacological strategy to mitigat…
Humanin
Humanin and MOTS-c Attenuate Atrial Fibrillation by Suppressing Fibrosis and Mitochondrial Dysfunction.
Humanin improved the rotenone-induced reactive oxygen species formation in PC12 cells by modulating the SIRT3…
Humanin Restores Metabolic Hormone Homeostasis of Leptin, Ghrelin, Irisin and Asprosin in Streptozotocin-Indu…
Neuroprotective Effect of Intraperitoneal Humanin-G in Retinal Degeneration of Royal College of Surgeons Rats.
+1 more
About Foxo4-DRI
D-retro-inverso peptide that disrupts Foxo4/p53 interaction in senescent cells; restores p53-mediated apoptosis selectively in senescent cells; clears cellular "zombie cells"
About Humanin
Mitochondria-derived peptide; binds gp130 receptor, activates STAT3/JAK pathway; inhibits BAX-mediated apoptosis; improves insulin sensitivity
Information below reflects published research data only — not medical advice. Consult a qualified provider before use.
Foxo4-DRI
Under clinical review
Being verified by our medical team before we display contraindications for this peptide.
Humanin
No established clinical contraindications. This is an investigational compound with limited human data and has not been evaluated by the FDA for safety in this context. Consult a qualified clinician.
Foxo4-DRI
Humanin
Where to source these peptides
Foxo4-DRI
14 listed
Browse directory →
Providers offeringHumanin
10 listed
Browse directory →
PeptideBase lists providers for educational research purposes only. Always consult a qualified healthcare professional before obtaining or using any peptide.
More Longevity & Cellular Comparisons
Browse all peptides →Educational research tools — not medical advice.
Cite this page
Data last updated August 26, 2026
Free to reference and republish with attribution to PeptideBase. Choose a format:
PeptideBase. (2026). Foxo4-DRI vs Humanin — Per-mg Price Comparison. Retrieved September 11, 2026, from https://peptidebase.io/peptides/compare/foxo4-dri/humanin