Home›Research›Compare›Foxo4-DRI vs Humanin
Peptide ComparisonFoxo4-DRI vs Humanin
Both are Longevity & Cellular peptides.
Foxo4-DRI
Foxo4-D-Retro-Inverso
Half-life: Unknown
13 providers listed
Humanin
HN
Half-life: ~2-4 hours
9 providers listed
Humanin carries stronger published evidence (Cohort study, 11 key studies) than Foxo4-DRI (Review, 3); both are research compounds.
Foxo4-DRI
Evidence
Half-life
Unknown
Humanin
Evidence
Half-life
~2-4 hours
| Your goal | Better option |
|---|---|
| Stronger clinical evidence | Humanin |
| More provider options (13 vs 9) | Foxo4-DRI |
Research summary only — not medical advice. Consult a qualified provider before making any decisions.
Foxo4-DRI
Humanin
Foxo4-DRI
Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging
Targeting the FOXO4-p53 axis by retro-inverso peptide senolytic agents: a pharmacological strategy to mitigat…
Rational design of a peptide inducing selective apoptosis of p53-high senescent cells by targeting the FOXO4-…
Humanin
Humanin and MOTS-c Attenuate Atrial Fibrillation by Suppressing Fibrosis and Mitochondrial Dysfunction.
Humanin Mitigates Aβ-Induced Retinal Pigment Epithelium Injury via AMPK-Beclin1-Dependent Mitophagy.
Humanin Restores Metabolic Hormone Homeostasis of Leptin, Ghrelin, Irisin and Asprosin in Streptozotocin-Indu…
Mitochondrial-derived Peptides and Cytoprotection in ARDS: Emerging Therapeutic Promise of Humanin.
+7 more
About Foxo4-DRI
D-retro-inverso peptide that disrupts Foxo4/p53 interaction in senescent cells; restores p53-mediated apoptosis selectively in senescent cells; clears cellular "zombie cells"
About Humanin
Mitochondria-derived peptide; binds gp130 receptor, activates STAT3/JAK pathway; inhibits BAX-mediated apoptosis; improves insulin sensitivity
Information below reflects published research data only — not medical advice. Consult a qualified provider before use.
Foxo4-DRI
Under clinical review
Being verified by our medical team before we display contraindications for this peptide.
Humanin
No established clinical contraindications. This is an investigational compound with limited human data and has not been evaluated by the FDA for safety in this context. Consult a qualified clinician.
Foxo4-DRI
Humanin
Not enough vendor pricing yet.
Where to source these peptides
Foxo4-DRI
13 listed
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Providers offeringHumanin
9 listed
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PeptideBase lists providers for educational research purposes only. Always consult a qualified healthcare professional before obtaining or using any peptide.
More Longevity & Cellular Comparisons
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Cite this page
Data last updated July 22, 2026
Free to reference and republish with attribution to PeptideBase. Choose a format:
PeptideBase. (2026). Foxo4-DRI vs Humanin — Per-mg Price Comparison. Retrieved July 22, 2026, from https://peptidebase.io/peptides/compare/foxo4-dri/humanin