What is the difference between GHRP-2 and Hexarelin?

GHRP-2: Synthetic hexapeptide that stimulates pulsatile growth hormone release from the anterior pituitary by acting on the ghrelin receptor (GHSR-1a). Hexarelin: Potent synthetic GHRP; strongest GH secretagogue in its class; also activates CD36 scavenger receptor for cardioprotective effects

Is Hexarelin FDA approved?

Hexarelin is not evaluated or approved by the FDA. It is discussed for research and educational purposes only, not as medical guidance.

How is GHRP-2 administered in research settings?

In research settings, GHRP-2 is typically administered via the subcutaneous or intramuscular routes. PeptideBase does not provide dosing or administration instructions.

How is Hexarelin administered in research settings?

In research settings, Hexarelin is typically administered via the subcutaneous route. PeptideBase does not provide dosing or administration instructions.

Home›Research›Compare›GHRP-2 vs Hexarelin

Peptide Comparison

GHRP-2 vs Hexarelin

Name: GHRP-2 vs Hexarelin — Per-mg Price Comparison
Creator: PeptideBase
License: https://peptidebase.io/terms

Both are GH / IGF Axis peptides.

GHRP-2

Growth Hormone Releasing Peptide 2

PerformanceUnder clinical reviewResearch Only

Half-life: 15–60 minutes

41 providers listed

Full GHRP-2 profile →

Hexarelin

Examorelin

PerformanceNot EvaluatedResearch Only

Half-life: ~30-60 minutes

22 providers listed

Full Hexarelin profile →

Bottom line

Hexarelin carries stronger published evidence (RCT, 2 key studies) than GHRP-2 (Cohort study, 2); both are research compounds.

Quick Verdict

GHRP-2

Evidence

Observational

Half-life

15–60 minutes

Hexarelin

Evidence

Emerging Clinical

Half-life

~30-60 minutes

Which One Should You Choose?

Your goal	Better option
Stronger clinical evidence	Hexarelin
Lower typical price per mg	GHRP-2
More provider options (41 vs 22)	GHRP-2

Research summary only — not medical advice. Consult a qualified provider before making any decisions.

Side-by-Side Comparison

GHRP-2

Hexarelin

Mechanism Family

GH / IGF Axis

Half-life

15–60 minutes

~30-60 minutes

FDA Status

Under clinical review

not evaluated

Admin Routes

subcutaneous, intramuscular

subcutaneous

Availability

Research Only

Providers

41 listed

22 listed

FDA Update

Under clinical review

—

Avail. Notes

Approved for diagnostic GH stimulation testing in Japan (Kaken Pharma) but NOT FDA-approved. Listed on the FDA Category 2 'significant safety risks' bulk-substances list (503B designation, added September 2023). WADA prohibited. Research chemical in US.

Potent hexapeptide GH secretagogue. No FDA approval anywhere. Not on FDA Category 1 or Category 2 list. WADA prohibited. More potent GH pulse than GHRP-6. Research use only.

Research Evidence

GHRP-2

ObservationalCohort study · 2 key studies · most recent 2020

Hexarelin

Emerging ClinicalRCT · 2 key studies · dated evidence base — most recent 2001

Research Citations

GHRP-2

Cohort2020 · Endocrine Journal

Preoperative growth hormone (GH) peak values during a GH releasing peptide-2 test reflect the severity of hyp…

Review2014 · Neurologia Medico-Chirurgica

Adult growth hormone deficiency: current concepts

Hexarelin

RCT2001 · Journal of Clinical Endocrinology and Metabolism

Endocrine activities of ghrelin, a natural growth hormone secretagogue (GHS), in humans: comparison and inter…

RCT1996 · Clinical Endocrinology

The effect of repeated administration of hexarelin, a growth hormone releasing peptide, and growth hormone re…

About GHRP-2

Synthetic hexapeptide that stimulates pulsatile growth hormone release from the anterior pituitary by acting on the ghrelin receptor (GHSR-1a). Commonly stacked with GHRH analogs such as CJC-1295 or Sermorelin to amplify GH output synergistically.

Research Areas

potent GH release via GHS-R1a agonismco-stimulation of cortisol and prolactin (non-selective profile)synergistic GH amplification when combined with GHRH analogsvalidated diagnostic GH stimulation agent (Japan clinical use)

About Hexarelin

Potent synthetic GHRP; strongest GH secretagogue in its class; also activates CD36 scavenger receptor for cardioprotective effects

Research Areas

potent GH secretion via GHS-R1a agonismcardiac tissue activity via CD36 receptor pathwaysmuscle recovery and lean mass supportreceptor desensitization with repeated use — cycling protocols studied

Safety Profile

Information below reflects published research data only — not medical advice. Consult a qualified provider before use.

GHRP-2

Absolute Contraindications

Under clinical review

Being verified by our medical team before we display contraindications for this peptide.

Suggested Monitoring

IGF-1Fasting glucoseHbA1cCortisolInsulin

GHRP-2 stimulates GH and cortisol release. Research protocols measure IGF-1 for GH axis response and baseline cortisol given the compound's adrenal stimulation. Glucose markers are standard given GH's effect on insulin sensitivity.

Hexarelin

Absolute Contraindications

Under clinical review

Being verified by our medical team before we display contraindications for this peptide.

Used Together?

GHRP-2

Corticosteroids
Research notes that GHRP-2 stimulates cortisol and ACTH release via the HPA axis. Combined use with corticosteroid medications may affect glucocorticoid regulation. Consult your prescriber before combining.

Price (per mg)

GHRP-2

$6.00/mg

$4.00 – $9.00 range

12 vendors

View price index →Find providers →

Hexarelin

$9.80/mg

$6.65 – $12.73 range

7 vendors

View price index →Find providers →

Find Providers

Where to source these peptides

Providers offering

GHRP-2

41 listed

Browse directory →

Providers offering

Hexarelin

22 listed

Browse directory →

PeptideBase lists providers for educational research purposes only. Always consult a qualified healthcare professional before obtaining or using any peptide.

More GH / IGF Axis Comparisons

Browse all peptides →

Educational research tools — not medical advice.

Cite this page

Data last updated July 27, 2026

Free to reference and republish with attribution to PeptideBase. Choose a format:

PeptideBase. (2026). GHRP-2 vs Hexarelin — Per-mg Price Comparison. Retrieved July 29, 2026, from https://peptidebase.io/peptides/compare/ghrp-2/hexarelin

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