Home / Combinations / Dihexa + Semax
CombinationCognitiveAnecdotal evidence
Dihexa + Semax
Memory & Cognitive Performance
Dihexa is researched as a potent hepatocyte growth factor (HGF/c-Met) modulator that promotes synaptogenesis and spatial memory. Semax, an ACTH analog, is investigated for BDNF upregulation and neuroprotective signaling in the brain. The combination is explored for its complementary routes to memory consolidation and cognitive resilience.
Stack components
DihexaCompound 01
SemaxCompound 02
2
Compounds
2
Sources on file
22
Providers carry all
Mechanism
What each compound is researched for on its own. Nothing here describes an interaction between them.
Compound 01
Dihexa
HGF/c-Met signaling modulator researched for potently facilitating synaptogenesis and spatial memory performance in animal models of cognitive decline.
Compound 02
Semax
ACTH analog researched for BDNF induction, NGF upregulation, and neuroprotective effects that support learning, memory consolidation, and stress resilience.
Composition
2 compounds · 1 research area
Stated as recorded. This page describes each compound separately and makes no claim that they act together.
Safety notes
Dihexa is highly potent and primarily characterized in preclinical research at very small amounts. Semax has an established research record with a favorable short-term safety profile in human trials. No human combination trial data is available.
Author-written. Not derived from any compound field, and not covered by the profile-integrity audit that gates the peptide pages.
Research references2 sources
Moderate
Dihexa (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) facilitates spatial learning and memory in rodents
J Pharmacol Exp Ther 2013
PeptideBase notePer-component source only — no combination study exists
no identifier on file
Moderate
Semax is a neuroprotective drug of the ACTH4-7 analogue family
Vestn Ross Akad Med Nauk 2014
PeptideBase notePer-component source only — no combination study exists
no identifier on file
Related combinations2 share an area
Cognitive
Selank + Semax: Cognitive Enhancement
Selank+Semax
Sleep · Cognitive
DSIP + Selank: Sleep & Anxiety Relief
DSIP+Selank
1 more would appear here. Cognitive has 3 combinations in total.
Educational use only
PeptideBase documents what compounds are researched together and what evidence exists for each one separately. It does not provide medical advice, diagnosis, treatment, prescribing guidance or dosing instructions. Last reviewed 23 Apr 2026.
PeptideBase documents what compounds are researched together and what evidence exists for each one separately. It does not provide medical advice, diagnosis, treatment, prescribing guidance or dosing instructions. Last reviewed 23 Apr 2026.