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Peptide Comparison

AOD-9604 vs Ghrelin

Both are GH / IGF Axis peptides.

AOD-9604

Advanced Obesity Drug 9604

Fat LossResearch Only

Half-life: 30–60 minutes

197 providers listed

Full AOD-9604 profile →
vs

Ghrelin

acyl ghrelin

PerformanceNot EvaluatedResearch Only

Half-life: ~24 min (initial), ~146 min (terminal)

3 providers listed

Full Ghrelin profile →
Bottom line

Ghrelin carries stronger published evidence (RCT, 5 key studies) than AOD-9604 (Animal, 1); both are research compounds.

Quick Verdict

AOD-9604

Half-life

30–60 minutes

Ghrelin

Half-life

~24 min (initial), ~146 min (terminal)

Which One Should You Choose?
Your goalBetter option
Stronger clinical evidenceGhrelin
Oral administration optionAOD-9604
More provider options (197 vs 3)AOD-9604

Research summary only — not medical advice. Consult a qualified provider before making any decisions.

Side-by-Side Comparison
AOD-9604
Ghrelin
Mechanism Family
GH / IGF Axis
GH / IGF Axis
Half-life
30–60 minutes
~24 min (initial), ~146 min (terminal)
FDA Status
nomination withdrawn
not evaluated
Admin Routes
subcutaneous, oral
subcutaneous, intravenous
Availability
Research Only
Research Only
Providers
197 listed
3 listed
Avail. Notes
HGH fragment 176-191. Drug development terminated 2007 (Phase 3 failure). FDA GRAS notice GRN 000792 for food ingredient use only — not a drug approval. No active NDA. Research chemical.
Research Evidence

AOD-9604

Animal · 1 key study · dated evidence base — most recent 2001

Ghrelin

RCT · 5 key studies · most recent 2026
Research Citations

About AOD-9604

AOD-9604 stimulates lipolysis and inhibits lipogenesis through mechanisms believed to be independent of the insulin-like growth factor pathway. It appears to mimic the fat-metabolising action of growth hormone without triggering the proliferative effects associated with full GH or GH-releasing peptides. Oral bioavailability has been observed in some formulations, making it of interest for non-injectable protocols.

Research Areas
selective fat tissue lipolysis via GH C-terminal fragment mechanismadipose metabolism stimulation without IGF-1 elevationoriginally developed to isolate GH lipolytic effect from growth effectssubcutaneous injection — reconstitution with bacteriostatic water required

About Ghrelin

Must be acylated at Ser3 (by GOAT enzyme) for GHSR-1a binding. Receptor activation in the pituitary stimulates GH release; hypothalamic action via NPY/AgRP neurons increases appetite and reduces energy expenditure.

Research Areas
GH stimulationappetite stimulationmetabolic regulationmuscle preservation
Safety Profile

Information below reflects published research data only — not medical advice. Consult a qualified provider before use.

AOD-9604

No established clinical contraindications. This is an investigational compound with limited human data and has not been evaluated by the FDA for safety in this context. Consult a qualified clinician.

Ghrelin

Absolute Contraindications

Under clinical review

Being verified by our medical team before we display contraindications for this peptide.

Price (per mg)

AOD-9604

$9.00/mg

$7.71$11.85 range

45 vendors

Ghrelin

Not enough vendor pricing yet.

Find Providers

Where to source these peptides

PeptideBase lists providers for educational research purposes only. Always consult a qualified healthcare professional before obtaining or using any peptide.

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Educational research tools — not medical advice.

Cite this page

Data last updated August 26, 2026

Free to reference and republish with attribution to PeptideBase. Choose a format:

PeptideBase. (2026). AOD-9604 vs Ghrelin — Per-mg Price Comparison. Retrieved August 26, 2026, from https://peptidebase.io/peptides/compare/aod-9604/ghrelin

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