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Peptide Comparison
AOD-9604 vs Sermorelin
Both are GH / IGF Axis peptides.
AOD-9604
Advanced Obesity Drug 9604
Half-life: 30–60 minutes
192 providers listed
Sermorelin
GHRH 1-29
Half-life: 10–20 minutes
443 providers listed
Bottom line
Sermorelin carries stronger published evidence (RCT, 2 key studies) than AOD-9604 (Animal, 1); both are research compounds.
Quick Verdict
AOD-9604
Evidence
Half-life
30–60 minutes
Sermorelin
Evidence
Half-life
10–20 minutes
Which One Should You Choose?
| Your goal | Better option |
|---|---|
| Stronger clinical evidence | Sermorelin |
| Less frequent dosing (longer half-life) | AOD-9604 |
| Oral administration option | AOD-9604 |
| More provider options (192 vs 443) | Sermorelin |
Research summary only — not medical advice. Consult a qualified provider before making any decisions.
Side-by-Side Comparison
Research Evidence
AOD-9604
Sermorelin
Research Citations
AOD-9604
Sermorelin
About AOD-9604
AOD-9604 stimulates lipolysis and inhibits lipogenesis through mechanisms believed to be independent of the insulin-like growth factor pathway. It appears to mimic the fat-metabolising action of growth hormone without triggering the proliferative effects associated with full GH or GH-releasing peptides. Oral bioavailability has been observed in some formulations, making it of interest for non-injectable protocols.
Research Areas
About Sermorelin
Sermorelin is a synthetic analogue of the first 29 amino acids of endogenous growth hormone-releasing hormone (GHRH). It binds to GHRH receptors on pituitary somatotrophs, stimulating pulsatile GH secretion in a physiological pattern that preserves the natural hypothalamic-pituitary feedback axis — contrasting with direct GH administration. Downstream IGF-1 elevation mediates many of its body composition, tissue-repair, and sleep quality effects.
Research Areas
Safety Profile
Information below reflects published research data only — not medical advice. Consult a qualified provider before use.
AOD-9604
Contraindications
Sermorelin
Contraindications
Suggested Monitoring
Sermorelin clinical protocols measure IGF-1 as the primary marker of GH axis response. Fasting glucose and insulin are standard baseline assessments given GH's effect on insulin sensitivity.
Used Together?
Sermorelin
Ipamorelin
Research suggests Sermorelin and Ipamorelin may produce complementary growth hormone release effects when combined. Sermorelin acts as a GHRH analogue via pituitary receptors, while Ipamorelin acts via ghrelin receptors — dual-pathway stimulation studied in GH optimization research.
Price (per mg)
AOD-9604
Sermorelin
Find Providers
Where to source these peptides
Providers offering
AOD-9604
192 listed
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Providers offering
Sermorelin
443 listed
Browse directory →
PeptideBase lists providers for educational research purposes only. Always consult a qualified healthcare professional before obtaining or using any peptide.
More GH / IGF Axis Comparisons
Browse all peptides →Educational research tools — not medical advice.
Cite this page
Data last updated June 29, 2026
Free to reference and republish with attribution to PeptideBase. Choose a format:
PeptideBase. (2026). AOD-9604 vs Sermorelin — Per-mg Price Comparison. Retrieved July 5, 2026, from https://peptidebase.io/peptides/compare/aod-9604/sermorelin