What is the difference between AOD-9604 and GHRP-6?

AOD-9604: AOD-9604 stimulates lipolysis and inhibits lipogenesis through mechanisms believed to be independent of the insulin-like growth factor pathway. GHRP-6: Ghrelin receptor agonist; stimulates pituitary GH release and increases appetite via hypothalamic ghrelin pathways

Is AOD-9604 FDA approved?

AOD-9604 is not evaluated or approved by the FDA. It is discussed for research and educational purposes only, not as medical guidance.

Is GHRP-6 FDA approved?

GHRP-6 is not evaluated or approved by the FDA. It is discussed for research and educational purposes only, not as medical guidance.

How is AOD-9604 administered in research settings?

In research settings, AOD-9604 is typically administered via the subcutaneous or oral routes. PeptideBase does not provide dosing or administration instructions.

How is GHRP-6 administered in research settings?

In research settings, GHRP-6 is typically administered via the subcutaneous or intranasal routes. PeptideBase does not provide dosing or administration instructions.

Home›Research›Compare›AOD-9604 vs GHRP-6

Peptide Comparison

AOD-9604 vs GHRP-6

Name: AOD-9604 vs GHRP-6 — Per-mg Price Comparison
Creator: PeptideBase
License: https://peptidebase.io/terms

Both are GH / IGF Axis peptides.

AOD-9604

Advanced Obesity Drug 9604

Fat LossNot EvaluatedResearch Only

Half-life: 30–60 minutes

192 providers listed

Full AOD-9604 profile →

GHRP-6

Growth Hormone Releasing Peptide-6

PerformanceNot EvaluatedResearch Only

Half-life: 15-60 minutes

40 providers listed

Full GHRP-6 profile →

Bottom line

GHRP-6 carries stronger published evidence (RCT, 2 key studies) than AOD-9604 (Animal, 1); both are research compounds.

Quick Verdict

AOD-9604

Evidence

Emerging Evidence

Half-life

30–60 minutes

GHRP-6

Evidence

Early Research

Half-life

15-60 minutes

Which One Should You Choose?

Your goal	Better option
Stronger clinical evidence	GHRP-6
Oral administration option	AOD-9604
Lower typical price per mg	GHRP-6
More provider options (192 vs 40)	AOD-9604

Research summary only — not medical advice. Consult a qualified provider before making any decisions.

Side-by-Side Comparison

AOD-9604

GHRP-6

Mechanism Family

GH / IGF Axis

Half-life

30–60 minutes

15-60 minutes

FDA Status

not evaluated

Admin Routes

subcutaneous, oral

subcutaneous, intranasal

Availability

Research Only

Providers

192 listed

40 listed

Avail. Notes

HGH fragment 176-191. Drug development terminated 2007 (Phase 3 failure). FDA GRAS notice GRN 000792 for food ingredient use only — not a drug approval. No active NDA. Research chemical.

Hexapeptide GH secretagogue. No FDA approval. Not on FDA Category 1 or Category 2 compounding list. WADA prohibited. Historical Phase 2 trials (Theratechnologies) but abandoned. Research chemical.

Research Evidence

AOD-9604

PreclinicalAnimal · 1 key study · through 2001

GHRP-6

ClinicalRCT · 2 key studies · through 1997

Research Citations

AOD-9604

Animal2001 · Endocrinology

The effect of the growth hormone fragment AOD9604 on adipose tissue

GHRP-6

Review1997 · European Journal of Endocrinology

Growth hormone-releasing peptides

RCT1995 · European Journal of Endocrinology

Growth hormone-releasing effect of oral growth hormone-releasing peptide 6 (GHRP-6) administration in childre…

About AOD-9604

AOD-9604 stimulates lipolysis and inhibits lipogenesis through mechanisms believed to be independent of the insulin-like growth factor pathway. It appears to mimic the fat-metabolising action of growth hormone without triggering the proliferative effects associated with full GH or GH-releasing peptides. Oral bioavailability has been observed in some formulations, making it of interest for non-injectable protocols.

Research Areas

selective fat tissue lipolysis via GH C-terminal fragment mechanismadipose metabolism stimulation without IGF-1 elevationoriginally developed to isolate GH lipolytic effect from growth effectssubcutaneous injection — reconstitution with bacteriostatic water required

About GHRP-6

Ghrelin receptor agonist; stimulates pituitary GH release and increases appetite via hypothalamic ghrelin pathways

Research Areas

GH release via GHS-R1a agonism — synergistic with GHRHpronounced appetite stimulation (ghrelin-mimetic effect)muscle recovery and GH pulse amplificationco-stimulation of cortisol and prolactin — less selective than ipamorelin

Safety Profile

Information below reflects published research data only — not medical advice. Consult a qualified provider before use.

AOD-9604

Contraindications

Pregnant Or Nursing

GHRP-6

Contraindications

Active CancerDiabetesHigh Cortisol

Suggested Monitoring

IGF-1Fasting glucoseHbA1cCortisolInsulin

GHRP-6 produces stronger cortisol and prolactin stimulation than selective GH peptides. Research protocols measure IGF-1 for GH axis response and baseline cortisol. Glucose markers are standard given GH's effect on insulin sensitivity.

Used Together?

GHRP-6

Corticosteroids
Research notes that GHRP-6 stimulates cortisol and ACTH release via the HPA axis. Combined use with corticosteroid medications may affect glucocorticoid regulation. Consult your prescriber before combining.

Price (per mg)

AOD-9604

$8.90/mg

$6.85 – $13.47 range

45 vendors

View price index →Find providers →

GHRP-6

$6.25/mg

$3.91 – $12.77 range

23 vendors

View price index →Find providers →

Find Providers

Where to source these peptides

Providers offering

AOD-9604

192 listed

Browse directory →

Providers offering

GHRP-6

40 listed

Browse directory →

PeptideBase lists providers for educational research purposes only. Always consult a qualified healthcare professional before obtaining or using any peptide.

More GH / IGF Axis Comparisons

Browse all peptides →

Educational research tools — not medical advice.

Cite this page

Data last updated July 3, 2026

Free to reference and republish with attribution to PeptideBase. Choose a format:

PeptideBase. (2026). AOD-9604 vs GHRP-6 — Per-mg Price Comparison. Retrieved July 5, 2026, from https://peptidebase.io/peptides/compare/aod-9604/ghrp-6

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