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HomeResearchCompareCJC-1295 DAC vs GHRP-6

Peptide Comparison

CJC-1295 DAC vs GHRP-6

Both are GH / IGF Axis peptides.

CJC-1295 DAC

CJC-1295 with DAC

Fat LossNot EvaluatedResearch Only

Half-life: 6–8 days

1 providers listed

Full CJC-1295 DAC profile →
vs

GHRP-6

Growth Hormone Releasing Peptide-6

PerformanceUnder clinical reviewResearch Only

Half-life: 15-60 minutes

39 providers listed

Full GHRP-6 profile →
Bottom line

CJC-1295 DAC carries stronger published evidence (RCT, 1 key studies) than GHRP-6 (Review, 1); both are research compounds.

Quick Verdict

CJC-1295 DAC

Half-life

6–8 days

GHRP-6

Half-life

15-60 minutes

Which One Should You Choose?
Your goalBetter option
Stronger clinical evidenceCJC-1295 DAC
Less frequent dosing (longer half-life)CJC-1295 DAC
Lower typical price per mgGHRP-6
More provider options (1 vs 39)GHRP-6

Research summary only — not medical advice. Consult a qualified provider before making any decisions.

Side-by-Side Comparison
CJC-1295 DAC
GHRP-6
Mechanism Family
GH / IGF Axis
GH / IGF Axis
Half-life
6–8 days
15-60 minutes
FDA Status
not evaluated
Under clinical review
Admin Routes
subcutaneous
subcutaneous, intranasal
Availability
Research Only
Research Only
Providers
1 listed
39 listed
FDA Update
Under clinical review
Avail. Notes
Long-acting GHRH analog with a Drug Affinity Complex (DAC) modification. No FDA approval. Not on the FDA 503A bulks list. WADA-prohibited as a growth hormone releasing factor. Sold as a research chemical only.
Hexapeptide GH secretagogue. No FDA approval. Listed on the FDA Category 2 'significant safety risks' bulk-substances list (503B designation, added September 2023). WADA prohibited. Historical Phase 2 trials (Theratechnologies) but abandoned. Research chemical.
Research Evidence

CJC-1295 DAC

RCT · 1 key study · dated evidence base — most recent 2006

GHRP-6

Review · 1 key study · dated evidence base — most recent 1997
Research Citations

About CJC-1295 DAC

CJC-1295 DAC is a GHRH analog carrying a Drug Affinity Complex (DAC) modification that binds covalently to circulating albumin, greatly extending its plasma half-life relative to unmodified or short-acting GHRH analogs. Through this albumin binding it acts as a long-lasting agonist at pituitary GHRH receptors, associated in research with sustained growth hormone and downstream IGF-1 elevation. This contrasts with the non-DAC form (Mod GRF 1-29), whose action is measured in minutes rather than days.

Research Areas
GH and IGF-1 elevation studied in a single-dose human PK trialsustained GHRH-receptor agonism via albumin bindingextended plasma half-life relative to short-acting GHRH analogsbody-composition and GH-axis research contextssubcutaneous administration in published research

About GHRP-6

Ghrelin receptor agonist; stimulates pituitary GH release and increases appetite via hypothalamic ghrelin pathways

Research Areas
GH release via GHS-R1a agonism — synergistic with GHRHpronounced appetite stimulation (ghrelin-mimetic effect)muscle recovery and GH pulse amplificationco-stimulation of cortisol and prolactin — less selective than ipamorelin
Safety Profile

Information below reflects published research data only — not medical advice. Consult a qualified provider before use.

CJC-1295 DAC

Warnings & Cautions
Active malignancy — caution (GH/IGF-1 is mitogenic)Pregnancy — cautionKnown hypersensitivityGlucose intolerance / insulin resistance

Class-based (investigational)

Suggested Monitoring
IGF-1Fasting glucoseHbA1cInsulin

Research protocols routinely measure IGF-1 to track GH axis activity before and during use. Fasting glucose and insulin are monitored because GH elevation can reduce insulin sensitivity over time.

Regulatory Notes

globalWADA

This compound falls under WADA Prohibited List category S2 (Peptide Hormones, Growth Factors, Related Substances and Mimetics), prohibited at all times for competing athletes.

source

GHRP-6

Absolute Contraindications

Under clinical review

Being verified by our medical team before we display contraindications for this peptide.

Suggested Monitoring
IGF-1Fasting glucoseHbA1cCortisolInsulin

GHRP-6 produces stronger cortisol and prolactin stimulation than selective GH peptides. Research protocols measure IGF-1 for GH axis response and baseline cortisol. Glucose markers are standard given GH's effect on insulin sensitivity.

Used Together?

GHRP-6

  • Corticosteroids

    Research notes that GHRP-6 stimulates cortisol and ACTH release via the HPA axis. Combined use with corticosteroid medications may affect glucocorticoid regulation. Consult your prescriber before combining.

Price (per mg)

CJC-1295 DAC

$10.63/mg

$9.74$15.25 range

20 vendors

GHRP-6

$4.60/mg

$3.18$6.65 range

20 vendors

Find Providers

Where to source these peptides

PeptideBase lists providers for educational research purposes only. Always consult a qualified healthcare professional before obtaining or using any peptide.

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Educational research tools — not medical advice.

Cite this page

Data last updated August 26, 2026

Free to reference and republish with attribution to PeptideBase. Choose a format:

PeptideBase. (2026). CJC-1295 DAC vs GHRP-6 — Per-mg Price Comparison. Retrieved August 26, 2026, from https://peptidebase.io/peptides/compare/cjc-1295-dac/ghrp-6

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