Home›Research›Compare›CJC-1295 DAC vs Sermorelin
Peptide ComparisonCJC-1295 DAC vs Sermorelin
Both are GH / IGF Axis peptides.
CJC-1295 DAC
CJC-1295 with DAC
Half-life: 6–8 days
1 providers listed
Sermorelin
GHRH 1-29
Half-life: 10–20 minutes
449 providers listed
CJC-1295 DAC has a longer half-life than Sermorelin, so it generally needs less frequent dosing.
CJC-1295 DAC
Half-life
6–8 days
Sermorelin
Half-life
10–20 minutes
| Your goal | Better option |
|---|---|
| Stronger clinical evidence | Sermorelin |
| Less frequent dosing (longer half-life) | CJC-1295 DAC |
| Lower typical price per mg | Sermorelin |
| More provider options (1 vs 449) | Sermorelin |
Research summary only — not medical advice. Consult a qualified provider before making any decisions.
CJC-1295 DAC
Sermorelin
Sermorelin
The GH response to low-dose bolus growth hormone-releasing hormone (GHRH(1-29)NH2) is attenuated in patients…
The relative roles of continuous growth hormone-releasing hormone (GHRH(1-29)NH2) and intermittent somatostat…
A new era of doping? Use of peptide and peptide-analog drugs in recreational and professional sport and bodyb…
About CJC-1295 DAC
CJC-1295 DAC is a GHRH analog carrying a Drug Affinity Complex (DAC) modification that binds covalently to circulating albumin, greatly extending its plasma half-life relative to unmodified or short-acting GHRH analogs. Through this albumin binding it acts as a long-lasting agonist at pituitary GHRH receptors, associated in research with sustained growth hormone and downstream IGF-1 elevation. This contrasts with the non-DAC form (Mod GRF 1-29), whose action is measured in minutes rather than days.
About Sermorelin
Sermorelin is a synthetic analogue of the first 29 amino acids of endogenous growth hormone-releasing hormone (GHRH). It binds to GHRH receptors on pituitary somatotrophs, stimulating pulsatile GH secretion in a physiological pattern that preserves the natural hypothalamic-pituitary feedback axis — contrasting with direct GH administration. Downstream IGF-1 elevation mediates many of its body composition, tissue-repair, and sleep quality effects.
Information below reflects published research data only — not medical advice. Consult a qualified provider before use.
CJC-1295 DAC
Class-based (investigational)
Research protocols routinely measure IGF-1 to track GH axis activity before and during use. Fasting glucose and insulin are monitored because GH elevation can reduce insulin sensitivity over time.
global — WADA
This compound falls under WADA Prohibited List category S2 (Peptide Hormones, Growth Factors, Related Substances and Mimetics), prohibited at all times for competing athletes.
sourceSermorelin
Under clinical review
Being verified by our medical team before we display contraindications for this peptide.
Sermorelin clinical protocols measure IGF-1 as the primary marker of GH axis response. Fasting glucose and insulin are standard baseline assessments given GH's effect on insulin sensitivity.
Sermorelin
Ipamorelin
Research suggests Sermorelin and Ipamorelin may produce complementary growth hormone release effects when combined. Sermorelin acts as a GHRH analogue via pituitary receptors, while Ipamorelin acts via ghrelin receptors — dual-pathway stimulation studied in GH optimization research.
CJC-1295 DAC
Sermorelin
Where to source these peptides
CJC-1295 DAC
1 listed
Browse directory →
Providers offeringSermorelin
449 listed
Browse directory →
PeptideBase lists providers for educational research purposes only. Always consult a qualified healthcare professional before obtaining or using any peptide.
More GH / IGF Axis Comparisons
Browse all peptides →Educational research tools — not medical advice.
Cite this page
Data last updated August 26, 2026
Free to reference and republish with attribution to PeptideBase. Choose a format:
PeptideBase. (2026). CJC-1295 DAC vs Sermorelin — Per-mg Price Comparison. Retrieved August 26, 2026, from https://peptidebase.io/peptides/compare/cjc-1295-dac/sermorelin