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Peptide Comparison

CJC-1295 DAC vs IGF-2

Both are GH / IGF Axis peptides.

CJC-1295 DAC

CJC-1295 with DAC

Fat LossNot EvaluatedResearch Only

Half-life: 6–8 days

15 providers listed

Full CJC-1295 DAC profile →
vs

IGF-2

Insulin-like Growth Factor 2

PerformanceNot EvaluatedResearch Only

Half-life: ~10-20 minutes

No providers listed yet

Full IGF-2 profile →
Bottom line

CJC-1295 DAC carries stronger published evidence (RCT, 1 key studies) than IGF-2 (Case series, 6); both are research compounds.

Quick Verdict

CJC-1295 DAC

Half-life

6–8 days

IGF-2

Half-life

~10-20 minutes

Which One Should You Choose?
Your goalBetter option
Stronger clinical evidenceCJC-1295 DAC
Less frequent dosing (longer half-life)CJC-1295 DAC
More provider options (15 vs 0)CJC-1295 DAC

Research summary only — not medical advice. Consult a qualified provider before making any decisions.

Side-by-Side Comparison
CJC-1295 DAC
IGF-2
Mechanism Family
GH / IGF Axis
GH / IGF Axis
Half-life
6–8 days
~10-20 minutes
FDA Status
not evaluated
not evaluated
Admin Routes
subcutaneous
subcutaneous, intramuscular
Availability
Research Only
Research Only
Providers
15 listed
None listed
Avail. Notes
Long-acting GHRH analog with a Drug Affinity Complex (DAC) modification. No FDA approval. Not on the FDA 503A bulks list. WADA-prohibited as a growth hormone releasing factor. Sold as a research chemical only.
Endogenous growth factor. No FDA-approved exogenous IGF-2 drug product. No NDA or IND for IGF-2 as primary active ingredient. Research use only.
Research Evidence

CJC-1295 DAC

RCT · 1 key study · dated evidence base — most recent 2006

IGF-2

Case series · 6 key studies · most recent 2026
Research Citations

About CJC-1295 DAC

CJC-1295 DAC is a GHRH analog carrying a Drug Affinity Complex (DAC) modification that binds covalently to circulating albumin, greatly extending its plasma half-life relative to unmodified or short-acting GHRH analogs. Through this albumin binding it acts as a long-lasting agonist at pituitary GHRH receptors, associated in research with sustained growth hormone and downstream IGF-1 elevation. This contrasts with the non-DAC form (Mod GRF 1-29), whose action is measured in minutes rather than days.

Research Areas
GH and IGF-1 elevation studied in a single-dose human PK trialsustained GHRH-receptor agonism via albumin bindingextended plasma half-life relative to short-acting GHRH analogsbody-composition and GH-axis research contextssubcutaneous administration in published research

About IGF-2

Binds IGF-1R and insulin receptor variant A; promotes anabolic signaling in muscle and fat; activates PI3K/Akt/mTOR pathway; different receptor binding profile than IGF-1

Research Areas
muscle growthfat metabolismtissue developmentrecovery
Safety Profile

Information below reflects published research data only — not medical advice. Consult a qualified provider before use.

CJC-1295 DAC

Warnings & Cautions
Active malignancy — caution (GH/IGF-1 is mitogenic)Pregnancy — cautionKnown hypersensitivityGlucose intolerance / insulin resistance

Class-based (investigational)

Suggested Monitoring
IGF-1Fasting glucoseHbA1cInsulin

Research protocols routinely measure IGF-1 to track GH axis activity before and during use. Fasting glucose and insulin are monitored because GH elevation can reduce insulin sensitivity over time.

Regulatory Notes

global — WADA

This compound falls under WADA Prohibited List category S2 (Peptide Hormones, Growth Factors, Related Substances and Mimetics), prohibited at all times for competing athletes.

source

IGF-2

Absolute Contraindications

Under clinical review

Being verified by our medical team before we display contraindications for this peptide.

Price (per mg)

CJC-1295 DAC

$11.94/mg

$8.85 – $17.19 range

25 vendors

IGF-2

Not enough vendor pricing yet.

Find Providers

Where to source these peptides

PeptideBase lists providers for educational research purposes only. Always consult a qualified healthcare professional before obtaining or using any peptide.

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Educational research tools — not medical advice.

Cite this page

Data last updated October 26, 2026

Free to reference and republish with attribution to PeptideBase. Choose a format:

PeptideBase. (2026). CJC-1295 DAC vs IGF-2 — Per-mg Price Comparison. Retrieved October 27, 2026, from https://peptidebase.io/peptides/compare/cjc-1295-dac/igf-2

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