FGF-1 vs PTD-DBM

Binds all four FGFR subtypes (broadest binding of FGF family). Activates MAPK and PI3K downstream pathways. Promotes fibroblast proliferation, angiogenesis, and hair follicle cycling into anagen phase.

A member of the fibroblast growth factor family that promotes cell growth, tissue repair, and angiogenesis across multiple cell types. Studied for wound healing, hair follicle stimulation, and skin rejuvenation.

Contains a protein transduction domain enabling intracellular delivery. Disrupts Dishevelled-Axin protein interaction, preventing β-catenin degradation and activating Wnt target genes essential for hair follicle cycling and new follicle neogenesis.

A cell-penetrating peptide that activates Wnt/β-catenin signaling in hair follicle dermal papilla cells. Studied as a potential hair regeneration therapy acting through a mechanism distinct from minoxidil and finasteride.